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Liquid target for medical isotope F-18 production

An F-18, isotope technology, applied in the field of medical liquid targets, can solve the problems of inconvenient disassembly and assembly, high cost of consumables, complex liquid target structure, etc., and achieve the effect of reducing heat and highlighting substantive characteristics

Pending Publication Date: 2021-02-23
CHINA INSTITUTE OF ATOMIC ENERGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies of the prior art, the present invention proposes a liquid target for the production of medical isotope F-18, aiming at the problems of complex structure, bulky volume, multiple consumables, high cost and inconvenient assembly and disassembly of the liquid target in the prior art

Method used

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  • Liquid target for medical isotope F-18 production
  • Liquid target for medical isotope F-18 production
  • Liquid target for medical isotope F-18 production

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Embodiment 1: The production process of liquid target is as follows Image 6 shown

[0058] 1. Ventilation is connected to 4UW-1 (air release port), ventilation is connected to ASVO, and ventilation is connected to 4MWE=A-1 (peristaltic pump);

[0059] 2. Start the peristaltic pump A to pump oxygen-enriched water into the liquid target chamber;

[0060] 3. After the injection is completed, turn off the peristaltic pump A and turn off the ASVO;

[0061] 4. Ventilate and connect the bleed valve 4UW-2 (blocking port),

[0062] 5. Ventilation is connected to 4MWE=A-2 (blocking);

[0063] 6. Turn on the beam, and adjust the center position of the beam to the center of the target through the measurement signals of the four fans installed in front of the target and the measurement signal of the target itself. After the beam irradiates oxygen-enriched water for about 2 hours, observe the pressure at any time Gauge read off beam current;

[0064] 7. Vent and connect the pro...

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Abstract

The invention discloses a liquid target for medical isotope F-18 production. According to the present invention, water cooling is adopted to replace helium cooling, so that the structure is simplified. As the own spaces of a beam limiting flange, a connecting flange and a target body are fully utilized, no extra space is occupied independently, water channels are formed in the beam limiting flange, the connecting flange and the target body, and a helium cooling device does not need to be specially arranged between the front end of the target body and the beam limiting flange so as to cool a target window (a Half membrane), so that the length of the liquid target is shortened, and the structure is simplified. According to the present invention, after one or more elements are omitted, all original functions are still kept. During disassembly, only a first hoop needs to be disassembled, all parts at the right side of the first hoop can be integrally taken down and put into a waste box toremove the radiation, and meanwhile, an accelerator end cannot be exposed in the air for a long time to be oxidized due to overlong disassembly time, and the radiation time of workers by a beam current due to inconvenient disassembly and assembly is effectively shortened.

Description

technical field [0001] The invention belongs to the technical field of medical liquid targets, in particular to a liquid target produced by medical isotope F-18. Background technique [0002] The short-lived radioactive isotopes such as 15O, 11C, 13N, and 18F produced by small medical cyclotrons are themselves components of the body. The above-mentioned nuclides produced by the nuclear reaction of the production target are chemically synthesized through a synthetic module box. Various radioactive drugs participate in the human body. metabolism, while F-18's synthetic drug, 18F-FDG, mimics glucose metabolism. The application of 18FDG and PET-CT imaging can detect the primary and metastatic lesions of the whole body tumors early, and accurately judge the benign and malignant ones, so as to correctly guide clinical treatment decisions. [0003] The liquid target is a mechanism that completes nuclear reactions and generates positron nuclides. The beam enters the corresponding t...

Claims

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Application Information

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IPC IPC(8): H05H6/00G21G1/10
CPCG21G1/10H05H6/00
Inventor 王飞宋国芳贾先禄杨光侯世刚张贺王景峰黄鹏王雷朱晓锋刘景源
Owner CHINA INSTITUTE OF ATOMIC ENERGY
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