Composition with auxiliary protection effect on gastric mucosal injury and application

A technology for gastric mucosal damage and protection, applied in the direction of application, drug combination, medical preparations containing active ingredients, etc., to achieve the effects of protection from alcohol damage, pleasant taste, improvement or protection of gastric mucosal health

Pending Publication Date: 2021-04-13
山西康欣药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Currently on the market, health food that combines edible fungi extracts and nationally regulated medicinal and food homologous substance extracts to protect / improve gastric mucosal health is still rare. Products that protect / improve the health of gastric mucosa based on medicinal and food homologous substances have broad application prospects

Method used

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  • Composition with auxiliary protection effect on gastric mucosal injury and application
  • Composition with auxiliary protection effect on gastric mucosal injury and application
  • Composition with auxiliary protection effect on gastric mucosal injury and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The components were mixed according to the weight shown in Table 1 to prepare a composition with auxiliary protective effect on gastric mucosal injury.

[0032] Table 1 The composition of health food

[0033]

[0034]

[0035] 1. The ethanol-induced acute injury experiment of gastric mucosa in rats was carried out on the above three prescriptions to evaluate the protective effect of the prescriptions

[0036] Experimental animals: SPF-grade male SD rats, weighing 180-220 g, were purchased from the Experimental Animal Management Department of Shanghai Institute of Family Planning Science, Animal Qualification Certificate SCXK (Shanghai) 2018-0006.

[0037] Dose settings:

[0038] Health food of the present invention is according to human body dosage 4.5g / day, and human body weight is calculated as 60kg, and then human dosage is 0.075g / kg day; Rat equivalent dose is calculated with 5 times (according to body surface area conversion), then rat dosage is 0.375g / kg ...

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PUM

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Abstract

The invention provides a composition with an auxiliary protection effect on gastric mucosal injury and application, and relates to the technical field of health care products. The composition comprises the following components in parts by weight of 30-60 parts of a water extract of hericium erinaceus sporocarp, 18-40 parts of a poria cocos water extract, 2-8 parts of a liquorice water extract and 10-25 parts of an astragalus membranaceus water extract. The composition disclosed by the invention can relieve gastric mucosal injury, and the inhibition rate can reach 40-67.5% under medium-concentration and high-concentration doses; the composition has the effects of protecting gastric mucosa epithelium from being damaged by ethanol and preventing ulcer; and the composition has a certain inhibition effect on helicobacter pylori. The composition disclosed by the invention has an obvious protective effect on ethanol-induced gastric mucosal acute injury, also has a good antibacterial effect on helicobacter pylori, is pleasant in taste, does not need to be added with seasoning auxiliary materials, and can be used for improving or protecting gastric mucosal health.

Description

technical field [0001] The invention belongs to the technical field of health care products, and in particular relates to a composition and its application which have an auxiliary protective effect on gastric mucosal damage. Background technique [0002] The stomach is an organ that plays a digestive role in the human body, and the nutrients needed for human life activities are mainly absorbed through the gastrointestinal tract. With the progress of the society and the times, people's pace of life is accelerated, coupled with the influence of bad living habits, the incidence of stomach disease is showing a rapid increase trend. According to the statistics of the World Health Organization in recent years, the incidence of stomach disease in the population is as high as 80%. %, and is growing at a rate of 17.43% per year, and the trend of gastric cancer is obvious, mostly in people over 35 years old, and the incidence of gastric cancer among young people aged 19 to 35 has doub...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L33/10A23L31/00A61K36/484A61P1/04A61P31/04
CPCA23L33/105A23L33/10A23L31/00A61K36/07A61K36/076A61K36/484A61K36/481A61P1/04A61P31/04A23V2002/00A23V2200/32A23V2250/21A23V2250/208A61K2300/00
Inventor 王昕王琪张冠楠吕升韩丽敏白丽强武江涛李巨龙闫大丁
Owner 山西康欣药业有限公司
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