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A kind of safe and non-toxic hot dyeing agent, preparation method and application

A safe, non-toxic, perm dyeing technology, applied in pharmaceutical formulations, dressing preparations, cosmetic preparations, etc., can solve the problems of keratin damage to hair cuticles, light dyed hair, and low color adhesion, and achieve good results. UV shielding effect, increase wash fastness, increase the effect of hair dyeing speed

Active Publication Date: 2021-12-03
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its strong alkaline environment will destroy the keratin of the hair scales, and it can only be dyed its own brown color instead of darker black, and the color adhesion is low
Mimicking Natural Human Hair Pigmentation with Synthetic Melanin, ACSCentral Science 2020 6(7), 1179-1188 mentioned the use of CuSO 4 +H 2 o 2 The Fenton-like system promotes the synthesis of melanin for hair dyeing, but there are still shortcomings such as lighter hair color, too single color, and metal ions
And there is still no dyeing and perming agent for hair dyeing and perm simultaneously on the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Preparation of agent A1: add ammonium thioglycolate, oleyl polyether, cocamidopropyl betaine, and add ethanolamine to adjust the pH to 9. The concentration of ammonium thioglycolate in the A1 agent reaches 16wt%, the concentration of oleyl polyether in the A1 agent reaches 1wt%, and the content of cocamidopropyl betaine in the A1 agent is 0.5wt%.

[0033] Preparation of agent A2: add cystine into Tris buffer solution with pH 8.5, stir until dissolved. Add dopamine hydrochloride, mix it with agent A1 at a ratio of 1:1 after stirring, and use it. The content of cystine in A2 agent is 0.5 mg / mL, and the content of dopamine hydrochloride is 1 mg / mL.

[0034] Preparation of agent B: add sodium bromate, and add an appropriate amount of hair conditioning agent laurylamine oxide. The content of sodium bromate in agent B is 8%wt, and the content of laurylamine oxide is 0.5wt%.

[0035] Preparation of agent C: add the thickener Pluronic F127 and the surfactant cocamidopropyl b...

Embodiment 2

[0038] The specific implementation process is the same as in Example 1, wherein the cystine content in the A2 dose is changed to 0.2 mg / mL.

Embodiment 3

[0040] The specific implementation process is the same as in Example 1, wherein the content of dopamine hydrochloride in the A2 dose is changed to 2 mg / mL.

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PUM

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Abstract

A safe and non-toxic dyeing and ironing agent, a preparation method and an application thereof belong to the field of special cosmetics. The ironing agent is a melanin dyeing and ironing agent that combines dyeing and ironing, and includes agent A1, agent A2, agent B and agent C. Among them, agent A1 is thioglycolic acid, thioglycolate salts or cysteine ​​reducing agent solution; agent A2 includes cystine or its derivatives, buffer solution and melanin precursor; agent B is sodium bromate or hydrogen peroxide Type oxidant solution; C agent includes melanin precursor substance, buffer solution and oxidant. The present invention uses melanin precursor substances for hair dyeing, and avoids the use of phenylenediamine substances with high carcinogenic and sensitizing risks. The invention combines the hair dyeing process with the perm process, realizes the integration of dyeing and perming, and does not need to perm first and then dye the hair twice to damage the hair. The invention uses melanin to adhere to the hair surface, and the melanin has good ultraviolet shielding effect, can protect hair keratin from yellowing and becoming brittle by ultraviolet rays, and protect damaged hair.

Description

technical field [0001] The invention belongs to the field of special cosmetics, and in particular relates to a synthetic melanin dyeing and ironing agent combined with dyeing and ironing and its application. Background technique [0002] Most people begin to decline from the age of 35, and the hair pigment cells begin to decline, and gray hair appears gradually. The population structure of today's society is gradually aging, and the demand for green and healthy hair dyes will also increase. However, all hair dyes currently on the market contain phenylenediamine substances, which are highly carcinogenic and sensitizing risk. Hairdressers may be at an increased risk of cancer due to frequent exposure to hair dye and other chemicals, according to the World Health Organization's International Agency for Research on Cancer. [0003] Polydopamine is a kind of natural melanin with excellent biocompatibility. Using polydopamine instead of phenylenediamine as the black precursor o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/20A61K8/22A61K8/41A61K8/44A61K8/46A61K8/49A61K8/64A61K8/66A61Q5/00A61Q5/06A61Q5/10
CPCA61K8/20A61K8/22A61K8/41A61K8/447A61K8/46A61K8/492A61K8/64A61K8/66A61Q5/004A61Q5/06A61Q5/10
Inventor 东为富郑宸李婷汪洋张正陈明清马丕明
Owner JIANGNAN UNIV
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