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Copolymer, preparation of copolymer and surgical instrument

A technology of surgical instruments and copolymers, applied in the field of copolymers, can solve the problems of patients with harmful tissue reactions, poor mechanical properties, slow reabsorption, etc., and achieve the effects of good absorption speed, easy degradation, and easy absorption

Pending Publication Date: 2021-04-13
SHENZHEN ANTMED CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, existing surgical instruments have poor mechanical properties and very slow resorption, so harmful tissue reactions may occur for the patient

Method used

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  • Copolymer, preparation of copolymer and surgical instrument
  • Copolymer, preparation of copolymer and surgical instrument
  • Copolymer, preparation of copolymer and surgical instrument

Examples

Experimental program
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Effect test

preparation example Construction

[0043] The present invention further proposes a preparation method of the above-mentioned copolymer, please refer to figure 1 , the preparation method of described copolymer comprises the following steps:

[0044] S10, under the condition of isolating the air, add the monomer A and the monomer B into the reaction flask respectively, and mix evenly to obtain the mixture;

[0045]It should be noted that the air isolation condition can be carried out in an atmosphere of an inert gas (such as nitrogen), or in a vacuum, for example in a sealed ampoule, in addition, it can also be carried out in a melt, a solution, an emulsion, In a suspension or the like, this can effectively prevent the oxidation of the monomer A and the monomer B by the oxygen in the air.

[0046] S20, adding a catalyst to the mixture, and reacting at 100° C. to 200° C. to obtain the copolymer.

[0047] In the above steps, the type of catalyst is not limited by the present invention, and esterification catalyst...

Embodiment 1

[0066] Add monomer A and monomer B into the ampoule respectively, mix well to obtain a mixture, then add stannous octoate to the mixture, wherein the molar ratio of monomer A to tin octoate is 10000:1, react at 150°C for 168h , to obtain a copolymer.

Embodiment 2

[0068] Add monomer A and monomer B into the ampoule respectively, mix well to obtain a mixture, then add stannous octoate to the mixture, wherein the molar ratio of monomer A to tin octoate is 10000:1, react at 110°C for 168h , to obtain a copolymer.

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Abstract

The invention discloses a copolymer, a preparation method of the copolymer and a surgical instrument, and relates to the technical field of copolymers. The copolymer is formed by copolymerizing a monomer A and a monomer B, the monomer A comprises lactone, the monomer B comprises a plurality of rings, and each ring comprises a group. The copolymer provided by the invention has good mechanical properties and good absorption speed, does not cause complications during degradation, and greatly relieves the pain of a patient.

Description

technical field [0001] The invention relates to the technical field of copolymers, in particular to a copolymer, a preparation method of the copolymer and a surgical instrument. Background technique [0002] With the continuous improvement of the medical level, more and more surgical instruments are used. Taking implants as an example, implantable medical devices are placed in body cavities caused by surgical operations or physiologically existing, and may last for 30 days. implanted items. In view of stricter public health requirements, the US FDA believes that items with a retention time of ≤ 30 days can also be considered as implants, and they will be managed as implants throughout the process. In clinical practice, most implants are processed by manufacturers through industrial sterilization, such as artificial joints, staplers, heart valves, etc. There are also a small number of implants, mainly orthopedic steel plates and steel nails, which require hospital processed...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08G63/64C08G63/78A61L31/06A61L31/14
CPCC08G63/64C08G63/78A61L31/06A61L31/14A61L31/148C08L67/00
Inventor 张平吴姗姗王五星
Owner SHENZHEN ANTMED CO LTD
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