Pulse ablation electrode assembly and pulse ablation catheter

Abstract

The invention relates to a pulse ablation electrode assembly which comprises a first electrode and a second electrode, the opposite ends of the two electrodes are protrusions which shrink gradually, and an insulating layer is arranged between the opposite ends of the two electrodes. The invention also relates to a pulse ablation catheter. According to the invention, the pulsed electric field can be used for ablating tissues more safely, more effectively and more conveniently.

Description

technical field [0001] The invention relates to a medical device, in particular to a pulse ablation electrode assembly and a pulse ablation catheter. Background technique [0002] Radiofrequency ablation and cryoablation are two commonly used clinical methods for the treatment of arrhythmias and tumors. Nowadays, pulsed electric field technology has also appeared. Pulsed electric field technology applies a short high voltage to tissue cells, which can generate a local high electric field of hundreds of volts per centimeter: the local high electric field destroys the cell membrane by creating pores in the cell membrane. An applied electric field at the membrane greater than the cellular threshold causes the pore not to close, and this electroporation is irreversible, thereby allowing the exchange of biomolecular material across the membrane, resulting in necrosis or apoptosis. Pulse irreversible electroporation ablation is different from radio frequency, freezing, microwave,...

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Problems solved by technology

If the voltage between the two electrodes is further reduced, the pulse intensity at the adjacent ends of the electrodes can meet the requirements, and the risk of scorching and scabbing caused by the adjacent ends of the two electrodes to human tissues can be prevented, that is, only between the outer edges of the two electrodes at the shortest distance If an electric field of consistent strength is generated in a small range, the pulse electric field at the end of the two electrodes away from each other and the side of the electrode is significantly lower than the required pulse electric field, and effective ablation cannot be achieved. In actual clinical pulse ablation, the effective pulse electric field space requires a volume that satisfies The pulsed electric field strength that meets the requirements is generated in the required electric field space. Usually, the electrodes inserted into the human body are small in size, the electric field space in the small range between the outer edges is too small, the ablation site is too small, the workload of linear ablation operation is huge, and the number of treatments is large. , the treatment effect is poor, and the ablation depth is not enough, and the overall ablation effect is poor or even ineffective. In order to ensure an effective electric field space, a large volume of electric field space is usually covered outside the entire electrode, and the electric field strength in this electric field space meets the ablation requirements. In the prior art, there is no effective technical solution to avoid the above-mentioned damage

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