Double-sleeve tracheal intubation device for rat

An endotracheal intubation and cannula technology, which is applied in the field of rat double cannula endotracheal intubation device, can solve the problems of difficulty in establishing an experimental model, easy concurrent infection, large wound surface and the like, achieves good fixation protection effect and improves survival rate , the effect of making simple and cost-effective

Pending Publication Date: 2021-05-28
中国人民解放军海军特色医学中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

We found in the establishment of a rat myocardial infarction scar model that the tracheotomy method has disadvantages such as large trauma area, multiple wounds, postoperative infection, and aggravated injury during the second intubation, resulting in low survival rate. Difficulties in model building

Method used

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  • Double-sleeve tracheal intubation device for rat
  • Double-sleeve tracheal intubation device for rat
  • Double-sleeve tracheal intubation device for rat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024]Example 1 Rat Double sleeve tracheal intubation device structure

[0025]according tofigure 1 The rat double sleeve tracheal intubation apparatus 100 includes an outer sleeve 1, an inner layer sleeve 2, and a steel wire 3. The outer sleeve 1 is used as an oral support, nested in the outer layer of the inner layer; the inner layer sleeve 2 is provided as a breathing tube, provided in the outer sleeve 1, as a respiratory pathway in rats; guided steel wire 3 as a Guide, guide the breathing tube insertion, and the insertion is completed, and the wire is pulled out, and the ventilation is connected to the ventilation structure.

[0026]according tofigure 2 The outer sleeve 1 includes a strut opening 11 that extends into the mouth chamber and two parts disposed on the outer grip end 12. The length of the support is 30 mm, which is a gradual structure. The angle of the front end is 30 ° and passivated the corner angle. The angle between the tail and the grip end is 120 °, the connection is...

Embodiment 2

[0030]Example 2 Experimental verification

[0031]1, materials and methods

[0032]Animals: 28 SD rats (Shanghai B.K. Company), 18, 10,000, weight 230g ± 20g.

[0033]The rat double sleeve tracheal cannula means were prepared according to the method described in Example 1.

[0034]2, steps:

[0035](1) Rat 3% pentobarbital sodium 50mg / kg intraperitoneal injection anesthesia, atropine 0.05mg / kg intramuscular injection to reduce respiratory secretions; after 10 ~ 15 minutes, rat supine, limbs and heads fixed in large Rat fixing on the wooden board.

[0036](2) Gently pull out and pick up the mouse tongue, use the amount of the mirror, and push the mouthpiece along the upper mouth of the rat, use its tip to gently pick up the soft bone, reveal the sound door.

[0037](3) Insert the guide wire into the breathing tube, and the tip is about 1 cm; the side wall of the tube is opened, and the tip of the tube is inserted between the two acoustic tapes in the rats; the front cut surface of the breathing tube ...

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PUM

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Abstract

The invention provides a double-sleeve tracheal intubation device for a rat. The double-sleeve tracheal intubation device comprises an outer-layer sleeve, an inner-layer sleeve and a guide steel wire. The outer-layer sleeve is used as an oral cavity opening pipe, is nested on the outer layer of the inner-layer sleeve, and comprises an opening end extending into an oral cavity and a holding end arranged on the outer side; the front end of the opening end is an inclined face, the included angle between the tail end of the opening end and the holding end is 100-120 degrees, and the thickness of the connecting position is 2-2.5 mm. The inner sleeve serves as a breathing tube, the front end of the inner sleeve has a certain angle and a passivated corner, and the tail end of the inner sleeve is provided with a breathing machine connecting mechanism; the guide steel wire is longer than the inner sleeve. The tracheal intubation assembly can effectively achieve rapid intubation, does not need a tracheotomy operation, and avoids complex surgical operation and extra damage to a rat. The use result shows that the method is small in damage to rats, stable, reliable and high in success rate, additional damage caused by exposure of multiple wounds in thoracotomy is avoided, secondary or multiple thoracotomy is facilitated, and the survival rate of animals is increased.

Description

Technical field[0001]The present invention belongs to the field of rat tracheal intubation, and in particular to a rat dual sleeve tracheal intubation apparatus that maintains a mechanical breathing in a rat chest cutting operation.Background technique[0002]Acute myocardial infarction is coronary acute and perseverance caused by sustained ischemia. The disease has more severe and lasting sternane pain, rest and nitrate drugs cannot completely alleviate, while serum myocardial enzyme activity increases and performs varying electrocardiogram, it can be confident, shock or heart failure It is often able to endanger life. Acute myocardial infarction is the most common in Europe and the United States. There are about 1.5 million people in the United States have a myocardial infarction. China has increased significantly in recent years, with a new year of 500,000, at least 2 million, therefore, therefore, the study of acute myocardial infarction is increasingly valued. Most of the animal ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D1/00
CPCA61D1/00
Inventor 马丽王震涛张凯杨翊方邹赢锌
Owner 中国人民解放军海军特色医学中心
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