Kit for rapidly detecting peripheral T cell lymphoma and use method thereof

Abstract

The invention belongs to the field of immunological detection, and relates to a kit, in particular to a kit for rapidly detecting peripheral T cell lymphoma and a use method of the kit. The kit comprises a reagent I and a reagent II, the reagent I comprises two groups of monoclonal antibody mixtures, and the first group of monoclonal antibody mixture comprises TRBC1, CD2, CD3, CD5, CD7, CD16, CD56, CD57 and CD45; the second group of monoclonal antibody mixture comprises the following components: TRBC1, TCR-gamma delta, CD3, CD8, CD4, CD7 and CD45; and the reagent II is hemolysin. The kit provided by the invention realizes the rapid and accurate detection of the peripheral T cell lymphoma (PTCL), is simple and convenient, greatly reduces the requirement on the sample size, and reduces the burden of a patient.

Description

technical field

[0001] The invention belongs to the field of immunological detection and relates to a kit, in particular to a kit for rapidly detecting peripheral T-cell lymphoma and a use method thereof. Background technique

[0002] Currently, the immunophenotypic diagnosis of T-cell lymphoma depends on the loss or abnormality of T-cell surface antigens. However, there are many types of T-cell lymphoma, the classification is complicated, and pathological diagnosis is difficult. These changes are often very weak, and the diagnosis of some T-cell lymphomas is difficult to clarify the nature only by HE and immunohistochemical staining; while flow cytometry can detect the absence, abnormal increase or decrease of T-cell antigen expression to assist T-cell lymphoma. T cell lymphoma diagnosis, but some T cell lymphomas have no obvious phenotypic abnormalities or activated reactive T cells during infection and T cells may also have phenotypic abnormalities in autoimmune diseases,...

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