Hibiseu manihot Lanti-aging composition, preparation method and application thereof
A composition, the technology of goldenflower sunflower, applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve the problems of few reports, achieve the removal of facial wrinkles and fine lines, reduce transepidermal water loss, and improve skin The effect of water content
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Embodiment 1
[0039] A preparation method of an anti-aging composition, comprising the steps of:
[0040] (1) Mince 1 kg of lemon peel, transfer it to a chromatographic column, pack the column, compact it, and elute with 90% volume fraction of ethanol aqueous solution at a flow rate of 2BV / h to obtain 1BV eluent;
[0041] (2) Add water to the eluent to obtain a mixed solution with an ethanol volume fraction of 80%;
[0042] (3) Dried 50kg of goldenflower sunflower and 10kg of rhodiola rosea, crushed, then added an appropriate amount of mixed solution to soak for 6 hours, and the liquid level should be slightly higher than the material; then transferred to a chromatography column, packed into a column, and compacted , with the mixed solution elution obtained in step (3), the flow rate is controlled at 2BV / h to obtain a 2BV extract;
[0043] (4) Centrifuge the extract, collect the supernatant, add dipropylene glycol, wherein the added amount of dipropylene glycol is 40% of the weight of the ...
Embodiment 2
[0045] A preparation method of an anti-aging composition, comprising the steps of:
[0046] (1) Mince 10 kg of lemon peel, transfer it to a chromatography column, pack the column, compact it, and elute with 95% ethanol aqueous solution at a flow rate of 1BV / h to obtain a 2BV eluent;
[0047] (2) Add water to the eluent to obtain a mixed solution with a volume fraction of ethanol of 60%;
[0048] (3) Dried 30kg of goldenflower sunflower and 20kg of rhodiola rosea, crushed, then added an appropriate amount of mixed solution to soak for 12 hours, and the liquid level should be slightly higher than the material; then transferred to a chromatography column, packed and compacted , with the mixed solution elution that step (3) obtains, flow rate is controlled at 1BV / h, obtains 3BV extract;
[0049] (4) Centrifuge the extract, collect the supernatant, add dipropylene glycol, wherein the added amount of dipropylene glycol is 60% of the weight of the supernatant; mix well, and then rem...
Embodiment 3
[0051] A preparation method of an anti-aging composition, comprising the steps of:
[0052](1) Mince 5 kg of lemon peel, transfer it to a chromatography column, pack the column, compact it, and elute with 92% ethanol aqueous solution at a flow rate of 1.5BV / h to obtain an eluent of 1.5BV;
[0053] (2) Add water to the eluent to obtain a mixed solution with a volume fraction of ethanol of 70%;
[0054] (3) Dried 40kg of goldenflower sunflower and 15kg of rhodiola rosea, crushed, then added an appropriate amount of mixed solution to soak for 8 hours, and the liquid level should be slightly higher than the material; then transferred to a chromatography column, packed into a column, and compacted , with the mixed solution elution obtained in step (3), the flow rate is controlled at 1.5BV / h to obtain a 2.5BV extract;
[0055] (4) Centrifuge the extract, collect the supernatant, add dipropylene glycol, wherein the added amount of dipropylene glycol is 50% of the weight of the super...
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