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Full-automatic cell production line

A fully automatic, production line technology, applied in tissue cell/virus culture devices, biochemical instruments, biomass post-processing, etc., can solve problems such as unstable operation, long continuous manual work time, and low efficiency

Active Publication Date: 2021-07-06
HELP STEM CELL INNOVATIONS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The whole process is manual operation, which has low efficiency, unstable operation, long continuous manual working hours, and difficulty in increasing output.

Method used

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  • Full-automatic cell production line
  • Full-automatic cell production line
  • Full-automatic cell production line

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0113] combined with figure 1 , a fully automatic cell production line, including culture area 1 (in order to save costs, its environment is set to a B-level environment at least) and an operation area 2 (in order to biosafety, its environment is set to an A-level environment). The culture area 1 is used for cell culture and cold storage; the operation area 2 is used for operations such as liquid exchange, centrifugation and freezing during cell culture. In this application, robot arms are used in the culture area 1 and the operation area 2 to realize the full automation of cell culture.

[0114] In order to better illustrate the technical solution of the present application, the following will be described in conjunction with specific examples:

[0115] attached Figure 2-3 About the training area

[0116] Such as figure 2 As shown, the cultivation area includes a B-level platform body, and the B-level platform body includes a cultivation area 1-2, a cold storage area 1-...

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PUM

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Abstract

The invention belongs to the technical field of biology, and relates to a full-automatic cell production line. The full-automatic cell production line comprises a culture zone and an operation area,; the culture zone comprises a B-level platform body, and the B-level platform body comprises a culture area, a refrigeration area and a robot provided with a motion track; the motion track of the robot is linearly arranged; the culture area, the refrigeration area and a manual delivery window are all arranged around the track and are all located in an operation area of the robot; a liquid storage table, a cell factory liquid changing device and a centrifugal bottle liquid changing device are integrated in the operation area; a transfer window is adopted between the culture area and the operation area to transfer materials; and the transfer window is provided with a transfer rotating disc and a transfer rotating disc driving mechanism, and the transfer rotating disc is provided with a zero position for the robot in the culture zone to pick and place the materials and a working position for a robotic arm in the operation area to pick and place the materials. The full-automatic cell production line is mainly used for full-automatic cell batch production.

Description

technical field [0001] The invention belongs to the field of biotechnology and relates to a fully automatic cell production line. Background technique [0002] Adherent cells adhere to the surface of the culture dish during culture and can continue to proliferate until the cells proliferate to cover the entire surface of the cell factory. At this time, the adherent cells can be peeled off from the cell factory. After centrifugation, point shock, separation, freezing and aliquoting, the cell production process is completed. [0003] The current cell culture process is all manually operated. After the culture medium and cells are poured into the cell factory, the cell factory is placed in the incubator for cultivation. After culturing for a period of time, it is necessary to remove the waste fluid of cell metabolism in the cell factory, and then add new culture fluid. The passage and cryopreservation of cells are also manual operations. After digestion and collection, the ce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00C12M1/36C12M1/34C12M1/26C12M1/24C12M1/12C12M1/00A01N1/02B04B9/08B04B9/10
CPCC12M23/06C12M23/14C12M23/48C12M23/52C12M27/16C12M29/00C12M29/26C12M33/04C12M33/08C12M33/10C12M37/00C12M37/04C12M41/48C12M41/00A01N1/0284B04B9/08B04B9/10C12M23/50C12M41/14
Inventor 张航周亚楠石小娟王倩王嘉显
Owner HELP STEM CELL INNOVATIONS CO LTD
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