Bacteriostatic and anti-inflammatory composition and preparation method and application thereof
A composition and mixture technology, applied in the application, drug combination, separation method and other directions, can solve the problems of destroying the micro-ecological environment of the private part, damaging the skin in the private part, and being very safe in the private part, so as to strengthen the antibacterial and anti-inflammatory effects, prevent the The growth of bacteria and the effect of protecting the microecological balance
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Embodiment 1
[0044] (1) In parts by weight, take 30 parts of Fructus Cnidii, 20 parts of Sophora flavescens, 20 parts of Cortex Phellodendri, 15 parts of capillary wormwood, 10 parts of chamomile and 5 parts of Saussurea involucrata, mix uniformly in 1 kg, pulverize, pass through a 12mm sieve, Then add 50kg of pure water and stir to obtain the mixture;
[0045] (2) The mixture is placed in a microfluidic extractor, and stirred for 20 min at 15° C., a rotation speed of 500 rpm, and a feed rate of 10 L / min, wherein the micropore diameter of the microfluidic extractor is 500 μm;
[0046] (3) The solution obtained removes the filter residue with a rotating speed of 2000rpm with a horizontal screw centrifuge, and uses a high-speed separator to remove other impurities with a rotating speed of 10000rpm to obtain a filtrate, and the filtrate is concentrated to 1kg through a reverse osmosis membrane with a pore size of 1nm to obtain the product .
Embodiment 2
[0048] (1) In parts by weight, weigh 60 parts of Fructus Cnidii, 10 parts of Sophora flavescens, 10 parts of Cortex Phellodendri, 10 parts of capillary, 5 parts of Chamomile and 5 parts of Saussurea involucrata, mix them uniformly, pulverize, pass through a 12mm sieve, Then add 30kg50wt% 1,3-butanediol aqueous solution and stir to obtain the mixture;
[0049] (2) The mixture is placed in a microfluidic extractor, and stirred for 30 minutes at 20° C., a rotating speed of 600 rpm, and a feed rate of 15 L / min, wherein the micropore diameter of the microfluidic extractor is 800 μm;
[0050] (3) the solution obtained removes the filter residue with the condition of rotating speed 3000rpm with a horizontal screw centrifuge, and adopts a high-speed separator to remove other impurities with the condition of rotating speed 8000rpm to obtain the filtrate, and the filtrate is concentrated to 1kg by the reverse osmosis membrane of 0.5nm aperture again, to obtain final product product.
Embodiment 3
[0052] (1) In parts by weight, take 20 parts of Fructus Cnidii, 40 parts of Sophora flavescens, 10 parts of Cortex Phellodendri, 10 parts of capillary wormwood, 10 parts of chamomile and 10 parts of Saussurea chinensis, mix 1kg evenly, pulverize, pass through a 12mm sieve, Then add 20kg 30wt% 1,2-propanediol aqueous solution and stir to obtain the mixture;
[0053] (2) The mixture is placed in a microfluidic extractor, and stirred for 40 min at 15° C., with a rotation speed of 300 rpm and a feed rate of 20 L / min, wherein the micropore diameter in the microfluidic extractor is 200 μm;
[0054] (3) the solution obtained removes the filter residue with the condition of rotating speed 4000rpm with a horizontal screw centrifuge, and adopts a high-speed separator to remove other impurities with the condition of rotating speed 12000rpm to obtain the filtrate, and the filtrate is concentrated to 1kg by the reverse osmosis membrane of 0.1nm aperture again, to obtain final product produ...
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