Biomarkers and kits for predicting the risk of developing ad in the elderly and their application

A risk and complex technology, applied in the field of risk biomarkers and kits, can solve the problems of time-consuming, labor-intensive, and expensive AD diagnostic methods, and achieve the effects of fast detection, low cost and high accuracy.
CN113125746BActive Publication Date: 2022-05-24HUAZHONG UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUAZHONG UNIV OF SCI & TECH
Publication Date
2022-05-24

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Abstract

The invention relates to the field of medicine, in particular to biomarkers and kits for predicting the risk of developing AD in the elderly and applications thereof. The biomarkers were included to include antiproliferative proteins, cytochrome b-c1 complex subunit 6, platelet glycoprotein Ib chain, and fibronectin. The biomarker can be used to evaluate the elderly, with high accuracy, fast detection speed, low cost, less trauma, and easy acceptance by the subjects, providing a scientific and effective diagnostic solution for AD. The kit can screen for AD in a large-scale elderly population, and only needs to collect peripheral blood to complete the detection, making it possible to screen a large-scale elderly population.
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Description

technical field

[0001] The present invention relates to the field of medicine, in particular to biomarkers and kits for predicting the risk of AD in the elderly and their applications. Background technique

[0002] Alzheimer's disease (AD) is a primary degenerative disease of the central nervous system and the most common type of dementia. The main clinical symptoms of AD are slow cognitive decline, including progressive loss of memory, logical reasoning ability, and language function, and finally develop into severe dementia.

[0003] At present, there is still a lack of early diagnosis measures for AD, and patients often have irreversible brain damage when they go to the doctor, resulting in poor treatment effect. Therefore, finding early risk factors is of great significance for early diagnosis and intervention.

[0004] Platelets and neurons have many biological similarities, therefore, platelets are ideal materials for finding peripheral biomarkers of central nervous ...

Claims

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