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Implanted instrument surface and manufacturing method thereof

A manufacturing method and device technology, which are applied to the surface of implanted devices and the field of manufacturing thereof, can solve the problems of poor microstructure surface uniformity, affect the function of the microstructure surface, affect the surface structure of the microstructure, etc., so as to increase the superhydrophobicity, Guaranteed stability and uniformity, improved hydrophobicity

Pending Publication Date: 2021-08-17
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the methods for preparing microstructured surfaces in the prior art are template method, coating method, etching method and laser method. Although these methods can prepare microstructures, they are affected by method limitations, and the uniformity of these microstructured surfaces Not good, especially when the laser method is used to make the microstructure surface, the high temperature of the laser will affect the structure of the microstructure surface, so as to affect the function of the microstructure surface
In addition, the existing technology relies solely on the microstructured surface to improve the performance of implanted devices. However, the microstructure has good antibacterial properties, but its hydrophobicity is still not enough, so that the surface of the microstructure will still interact with the liquid of human tissue. Thrombosis

Method used

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  • Implanted instrument surface and manufacturing method thereof
  • Implanted instrument surface and manufacturing method thereof
  • Implanted instrument surface and manufacturing method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0032] This embodiment discloses a method for manufacturing the surface of an implanted device, comprising the following steps,

[0033] S1: Use diamond polishing abrasive grains or alumina polishing grains with a particle size of 0.3μm to polish the surface of the metal instrument at a line speed of 4m / s and a pressure of 0.1MPa. The polishing time is 20min. Polish the surface of the metal instrument. The surface roughness of the final instrument is Ra<0.1μm.

[0034] S2: Using a femtosecond laser to etch the surface of the device polished by S1 to etch a microstructure surface, the microstructure surface has microstructures of at least two sizes, preferably, the microstructure surface is composed of an ordered submicron structure The surface is composed of a surface with a disordered nanoparticle structure, and further preferably, the ordered submicron structure surface includes a square groove structure and a rhombic groove structure. Wherein, during the etching of the fem...

Embodiment 2

[0038] This embodiment discloses a method for manufacturing the surface of an implanted device, comprising the following steps,

[0039] S1: Use diamond polishing abrasive grains or alumina polishing grains with a particle size of 6 μm to polish the surface of metal instruments at a linear speed of 7 m / s and a pressure of 0.4 MPa. The polishing time is 20 to 40 minutes. The roughness of the polished instrument surface Degree Ra<0.1μm.

[0040] S2: Using a femtosecond laser to etch the surface of the device polished by S1 to etch a microstructure surface, the microstructure surface has microstructures of at least two sizes, preferably, the microstructure surface is composed of an ordered submicron structure The surface is composed of a surface with a disordered nanoparticle structure, and further preferably, the ordered submicron structure surface includes a square groove structure and a rhombic groove structure. Wherein, during the etching of the femtosecond laser, the laser ...

Embodiment 3

[0044] This embodiment discloses a method for manufacturing the surface of an implanted device, comprising the following steps,

[0045] S1: Use diamond polishing abrasive grains or alumina polishing grains with a particle size of 0.5μm to polish the surface of the metal instrument at a line speed of 5m / s and a pressure of 0.3MPa. The polishing time is 30min. Polish the surface of the metal instrument. The surface roughness of the final instrument is Ra<0.1μm.

[0046] S2: Using a femtosecond laser to etch the surface of the device polished by S1 to etch a microstructure surface, the microstructure surface has microstructures of at least two sizes, preferably, the microstructure surface is composed of an ordered submicron structure The surface is composed of a surface with a disordered nanoparticle structure, and further preferably, the ordered submicron structure surface includes a square groove structure and a rhombic groove structure. Wherein, during the etching of the fem...

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Abstract

The invention relates to the technical field of medical instruments, in particular to an implanted instrument surface and a manufacturing method thereof. The manufacturing method comprises the following steps that S1, a metal instrument surface is polished; S2, femtosecond laser is adopted to etch the instrument surface polished in the S1, a microstructure surface is etched, and the microstructure surface is provided with microstructures of at least two sizes; S3, ultrasonic cleaning is conducted on the surface of the microstructure prepared in the S2 through absolute ethyl alcohol, and then the surface of the microstructure is cleaned through deionized water; and S4, hydroxylation treatment is conducted on the surface of the microstructure cleaned in the S3, then the surface of the microstructure is dried, and the surface of the implanted instrument is obtained. By means of the manufacturing method, the super-hydrophobic and self-cleaning antibacterial surface can be manufactured, and the surface of the implanted instrument has excellent super-hydrophobicity, antibacterial performance, self-cleaning performance and biocompatibility.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to an implanted device surface and a manufacturing method thereof. Background technique [0002] After the implanted device of modern medicine is implanted into the human body, the surface of the implanted device will come into contact with body fluid tissue, and then adhere to the tissue, resulting in contamination of the implanted device or infection of human tissue, and generation of thrombus, which is harmful to the implanted device and human body. There are serious dangers. [0003] At present, etching microstructures on the surface of implanted devices can isolate corrosive liquids to improve the biocompatibility of implanted devices. However, the methods for preparing microstructured surfaces in the prior art are template method, coating method, etching method and laser method. Although these methods can prepare microstructures, they are affected by method limitation...

Claims

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Application Information

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IPC IPC(8): A61L31/08A61L31/02A61L31/16B23K26/362B24C1/08B24C11/00C25F3/16
CPCA61L31/088A61L31/084A61L31/16A61L31/08A61L31/022C25F3/16B23K26/362B24C1/08B24C11/00A61L2300/404A61L2400/18
Inventor 王成勇罗彩君杜策之郑李娟
Owner GUANGDONG UNIV OF TECH
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