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Medical wet dressing with repairing function and preparation method thereof

A wet dressing and functional technology, applied in the field of medical skin care, can solve the problems of slow recovery of skin wounds, unhealed wounds, red and swollen wounds, etc., and achieve the effects of reducing skin wrinkles, reducing epidermal water permeability, and promoting the formation of new cells

Inactive Publication Date: 2021-08-27
吉林省国大生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the extensive use of antibiotics is prone to drug resistance, which leads to slow recovery of traumatic skin wounds, long-term wound healing, and even redness, swelling, oozing, and infection in the wounds

Method used

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  • Medical wet dressing with repairing function and preparation method thereof
  • Medical wet dressing with repairing function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A medical wet dressing with repairing function, including 4% glycerin, 2% hydroxyethyl cellulose, 1% xanthan gum, 1% luba gum, 0.3% triethanolamine, 0.2% nipol Gold Propyl Sodium, 3% Carbomer, 0.05% Disodium EDTA, 0.5% Recombinant Human Type III Collagen, 0.1% Sodium Hyaluronate, 1% Beta Glucan, 0.1% Corrective agent, balance is deionized water.

Embodiment 2

[0037] A preparation method of a medical moist dressing with repairing function, the steps are as follows:

[0038] (1) Add hydroxyethyl cellulose to part of the deionized water under stirring, after stirring and dispersing, heat part of the deionized water to 50-55°C, keep stirring at constant temperature, dissolve hydroxyethyl cellulose, and form hydroxyethyl cellulose Cellulose liquid;

[0039] (2) Add glycerin, xanthan gum, Luba gum, sodium propylparaben, carbomer, and disodium edetate to the hydroxyethyl cellulose liquid that is continuously stirred in step (1), and continue Keep stirring at constant temperature for 30 minutes to form an initial mixed solution;

[0040] (3) Disperse the recombinant human type III collagen, sodium hyaluronate, β-glucan, and flavoring agent in the remaining deionized water to form a spare solution;

[0041] (4) cooling the mixed solution in step (2) to room temperature, adding the standby solution in step (3) to the primary mixed solution...

Embodiment 3

[0045] Embodiment 3 skin sensitization test and acute toxicity test

[0046] 1. Experimental object:

[0047] Guinea pigs were taken, half male and half female, housed in separate cages of the same sex, and randomly divided into control group and experimental group.

[0048] 2. Experimental method:

[0049] 2.1 Acute skin sensitization test:

[0050] The guinea pigs were depilated on both sides of the back spine, and it was confirmed that the skin was intact without irritation after depilation.

[0051] Experimental group: take the dressing prepared in Example 2 (prepared according to the recipe in Example 1) and apply it evenly on the depilated area.

[0052] Control group: apply 1% 2.4-dinitrochlorobenzene solution.

[0053] The experimental group and the control group were applied once a day for 14 consecutive days.

[0054] 2.2 Acute skin toxicity test:

[0055] Cut or shave the hair on both sides of the back spine of the guinea pig without scratching the skin.

[0...

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Abstract

The invention provides a medical wet dressing with a repairing function. The medical wet dressing comprises 1%-5% of glycerin, 1%-4% of hydroxyethyl cellulose, 0.1%-2% of xanthan gum, 0.1%-2% of lubrajel, 0.1%-1% of triethanolamine, 0.01%-1% of sodium propyl paraben, 0.1%-3% of carbomer, 0.01%-1% of disodium ethylene diamine tetraacetate, 0.01%-1% of recombinant human III type collagen, 0.05%-0.2% of sodium hyaluronate, 0.1%-2% of beta glucan, 0.01%-1% of a flavoring agent and the balance deionized water. According to the medical wet dressing with the repairing function, the aging process of human skin can be relieved, the recombinant human III type collagen has good biological compatibility and cell adhesiveness, new cell formation can be promoted, hemostasis can be achieved, and the function of promoting epithelial cell growth is higher. The medical wet dressing can significantly reduce the water permeability of epidermis, reduce skin wrinkles, recover the barrier function of skin, accelerate the healing of various epidermis wounds and tissues such as burn, scald and phototherapy, and has a significant repair effect.

Description

technical field [0001] The invention belongs to the technical field of medical skin care, and in particular relates to a medical wet dressing with repairing function and a preparation method thereof. Background technique [0002] The skin is the outermost protective barrier of the human body, and it is constantly under various environmental pressures from physics, chemistry, microorganisms, radiation, etc. for 24 hours. Two of the most common manifestations of human skin over its life cycle are skin aging and skin damage. [0003] The manifestations of skin aging are diverse, including skin thinning, decreased elasticity, and wrinkles; decreased barrier function, increased transepidermal water loss, decreased sebum secretion, and easy drying; abnormal pigment metabolism, which can be lost or deposited; tumor tendency, such as basal cell carcinoma. Aging is an age-related degenerative disease of the body, which cannot be avoided, stopped and reversed by every individual. An...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0033A61L26/0014A61L26/0066A61L2300/252A61L2300/412C08L5/08C08L5/02C08L1/284C08L89/00C08L33/02C08L5/00
Inventor 刘东跃
Owner 吉林省国大生物工程有限公司
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