Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method and device for predicting vitrification resuscitation effect of human mature oocytes

A technology of vitrification and prediction method, applied in the direction of medical automatic diagnosis, treatment, health care informatics, etc., can solve the problems of physical and mental injury of patients, inability to form embryos, treatment costs and time wastage, so as to reduce the risk of surgical operation, Avoid wasting time and medical resources, and address poor repeatability

Active Publication Date: 2021-08-27
PEKING UNIV THIRD HOSPITAL
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The characteristics of oocytes themselves determine that they are extremely vulnerable to freezing damage, and may not be able to form embryos after thawing, and the oocyte retrieval operation itself has risks such as bleeding and infection, which will cause physical and mental harm to patients; on the other hand, if you give up Egg retrieval, the cost and time wasted in the process of early ovulation induction, and the super-physiological dose of estrogen in the body lead to a significant increase in the risk of ovarian hyperstimulation syndrome

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method and device for predicting vitrification resuscitation effect of human mature oocytes
  • Method and device for predicting vitrification resuscitation effect of human mature oocytes
  • Method and device for predicting vitrification resuscitation effect of human mature oocytes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] A method for predicting the vitrification recovery effect of human mature oocytes, comprising the following steps:

[0049] S10. Obtain the basic information of the woman, the number of large and medium follicles, the test results of sex hormones and infertility-related diseases, and the results of the semen examination of the man, and determine the method of sperm collection according to the semen test results of the man. Sperm collection methods include ejaculation, percutaneous epididymis / testicular aspiration, and percutaneous epididymis / testicular aspiration under a microscope.

[0050] The information obtained is obtained from the clinical history data and laboratory test results of both men and women before egg retrieval. The basic information of the woman includes the age of the woman, the duration of infertility, the test results of sex hormones including follicle stimulating hormone and estradiol, and the results of infertility-related diseases including wheth...

Embodiment 2

[0079] A device for predicting the vitrification recovery effect of human mature oocytes, comprising: a memory, a processor, and a computer program stored on the memory and operable on the processor, and the processor implements the computer program described in Embodiment 1 when executing the computer program the forecasting method described above.

[0080] Such as figure 1 As shown, the computer program stored on the memory includes the following functional modules:

[0081] A data collection module 10 , a prediction probability calculation module 20 of no embryo transfer, a cumulative live birth prediction probability calculation module 30 and a resuscitation effect prediction module 40 .

[0082] The data collection module 10 is used to obtain the basic information of the woman, the number of large and medium follicles on the day of application of follicle-stimulating drugs, the test results of sex hormones and the results of infertility-related diseases, and the results ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a human mature oocyte vitrification resuscitation effect prediction method and device. The prediction method comprises the steps: acquiring the basic information of women, the number of large and medium follicles in the application day of follicle maturation promoting medicine, sex hormone test results and infertility related disease examination results and semen examination results of men; calculating an embryo-free transplantable prediction probability P1 and a cumulative live production prediction probability P2 of the egg cell cryopreservation operation to be carried out at the time; and predicting the resuscitation effect according to the values of P1 and P2. The prediction device comprises a memory, a processor and a computer program which is stored in the memory and can run on the processor, wherein the processor implements the prediction method when executing the computer program. According to the method, the recovery effect of the egg cell cryopreservation operation to be carried out at the time is estimated according to clinical medical history data and test and examination results before egg collection of the couples and the women, a patient is helped to make reasonable decisions, unnecessary surgical operation risks are reduced as much as possible, and waste of time and medical resources is avoided.

Description

technical field [0001] The invention relates to the technical field of human assisted reproduction, more specifically, it relates to a method and a device for predicting the vitrification recovery effect of human mature oocytes. Background technique [0002] Assisted reproductive technology refers to the use of medical assistance to make infertile couples pregnant. Delayed childbearing age, environmental pollution, increased work pressure and other reasons make more and more couples need the help of assisted reproductive technology, and oocyte freezing is one of the important assisted reproductive technologies. [0003] During the IVF-ET treatment, if the man is unable to come to the hospital to collect sperm due to sudden illness or accident, masturbation or surgical sperm retrieval failure, or other unexpected sperm retrieval failures, or does not obtain enough sperm for assisted fertility treatment on the day of egg retrieval Emergency oocyte freezing for sperm, etc. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G16H20/00G16H50/20
CPCG16H50/30G16H20/00G16H50/20
Inventor 李蓉王洋牛子儒严杰郑晓英刘平乔杰
Owner PEKING UNIV THIRD HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com