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Disinfectant composition containing povidone iodine and application thereof

A technology of povidone-iodine and composition, applied in the field of medicine, can solve problems such as adverse reactions, and achieve the effects of preventing adsorption and osmosis, reducing irritation and improving stability

Active Publication Date: 2021-08-31
XIAMEN DAKAI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are certain adverse reactions during use

Method used

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  • Disinfectant composition containing povidone iodine and application thereof
  • Disinfectant composition containing povidone iodine and application thereof
  • Disinfectant composition containing povidone iodine and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 44

[0271]

Embodiment 45

[0273]

Embodiment 46

[0275]

[0276]

[0277] Method: Samples were prepared according to the examples listed in the prescriptions of Examples 44-46. The preparation method of 100mL povidone-iodine disinfectant is as follows: take an appropriate amount of water, add 5g of povidone-iodine to dissolve, and then add alkylaryl polyoxyethylene ether surfactants (nonoxynol, tyloxapol) pH Dissolve buffer (disodium hydrogen phosphate, citric acid) and osmotic pressure regulator (glycerol, sodium chloride), adjust pH to 3.0 with pH regulator (sodium hydroxide), add water to 100mL, and get ready.

[0278] Embodiment 44 is packaged in a brown PP material plastic bottle, embodiment 45 is packaged in a blue PET material plastic bottle, and embodiment 46 is packaged in a green PETG material plastic bottle.

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PUM

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Abstract

The invention belongs to the field of medicines, and relates to a disinfectant composition containing povidone iodine and application thereof. Specifically, the disinfectant composition containing povidone iodine comprises an effective amount of povidone iodine, two or more alkyl aryl polyoxyethylene ether surfactants, one or more pH buffer agents, one or more pH regulators and one or more osmotic pressure regulators, wherein the alkyl aryl polyoxyethylene ether surfactant least comprises nonoxynol and tyloxapol. The disinfectant composition disclosed by the invention can effectively reduce volatilization of iodine in the disinfectant composition and permeation and adsorption of the disinfectant composition to a plastic packaging material, reduces irritation during use, and has a good application prospect.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a disinfectant composition containing povidone-iodine and its application. The disinfectant composition is used for disinfection of hands, skin or mucous membranes. Background technique [0002] Iodine-containing disinfectants can be used to disinfect hands, skin, and mucous membranes, and can be diluted with water in proportion to be applied to certain parts and environments. [0003] All iodine-containing disinfectants are solutions, but iodine is an easily sublimable substance, and the effective iodine of the product is easily volatilized from the solution during storage. Through the plastic packaging material, the effective iodine content of the product decreases, thereby reducing the disinfection effect. The article "Factors Affecting the Stability of Povidone-Iodine Solution" published in "Journal of Modern Medicine and Health" indicates that the available iodine content in the povid...

Claims

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Application Information

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IPC IPC(8): A61K31/79A61K9/08A61K47/02A61K47/10A61K47/12A61K47/34A01N59/12A01P1/00A01P3/00A61P31/04A61P31/10A61P31/12A61P33/00
CPCA61K31/79A61K47/10A61K47/34A61K47/02A61K47/12A61K9/0014A61K9/08A61P31/04A61P31/10A61P31/12A61P33/00A01N59/12A01P3/00A01P1/00
Inventor 王迪
Owner XIAMEN DAKAI BIOTECH CO LTD