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A kind of disinfectant composition containing povidone iodine and its application

A technology of povidone-iodine and composition, which is applied in the field of medicine, can solve problems such as adverse reactions, achieve the effects of preventing adsorption and penetration, reducing irritation, and satisfying bactericidal effect

Active Publication Date: 2022-06-24
XIAMEN DAKAI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are certain adverse reactions during use

Method used

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  • A kind of disinfectant composition containing povidone iodine and its application
  • A kind of disinfectant composition containing povidone iodine and its application
  • A kind of disinfectant composition containing povidone iodine and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 44

[0260]

Embodiment 45

[0262]

Embodiment 46

[0264]

[0265]

[0266] Method: Prepare the samples according to the examples listed in the recipes of Examples 44-46, respectively. The preparation method of 100mL povidone-iodine disinfectant is as follows: take an appropriate amount of water, add 5g of povidone-iodine to dissolve, and then add alkyl aromatic polyoxyethylene ether surfactants (nonoxynol, tyloxapol) pH Dissolve the buffer (disodium hydrogen phosphate, citric acid) and the osmotic pressure regulator (glycerol, sodium chloride), adjust the pH to 3.0 with the pH regulator (sodium hydroxide), and add water to 100 mL, that is.

[0267] Example 44 was packaged in a brown PP plastic bottle, Example 45 was packaged in a blue PET plastic bottle, and Example 46 was packaged in a green PETG plastic bottle.

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PUM

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Abstract

The invention belongs to the field of medicine, and relates to a disinfectant composition containing povidone-iodine and its application. Specifically, the disinfectant composition of povidone iodine, which comprises: an effective amount of povidone iodine, two or more alkylaryl polyoxyethylene ether surfactants, one or more pH buffering agent, one or more pH regulators, and one or more osmotic pressure regulators, wherein the alkylaryl polyoxyethylene ether surfactants include at least nonoxynol and Tylosan moor. The invention can effectively reduce the volatilization of iodine in the disinfectant composition and the penetration and adsorption of plastic packaging materials, reduce the irritation during use, and has good application prospects.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a disinfectant composition containing povidone-iodine and use thereof. The disinfectant composition is used for disinfection of hands, skin or mucous membranes. Background technique [0002] Iodine-containing disinfectants can be used for disinfection of hands, skin and mucous membranes, and can be diluted with water in proportion to disinfect certain parts and environments. [0003] All iodine-containing disinfectants are solutions, but iodine is a substance that is easy to sublime. During the storage process of the product, the available iodine is easily volatilized from the solution. Through the plastic packaging material, the effective iodine content of the product is reduced, thereby reducing the disinfection effect. The article "Factors Affecting the Stability of Povidone Iodine Solution" published in "Journal of Modern Medicine and Hygiene" suggests that the content of available iod...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/79A61K9/08A61K47/02A61K47/10A61K47/12A61K47/34A01N59/12A01P1/00A01P3/00A61P31/04A61P31/10A61P31/12A61P33/00
CPCA61K31/79A61K47/10A61K47/34A61K47/02A61K47/12A61K9/0014A61K9/08A61P31/04A61P31/10A61P31/12A61P33/00A01N59/12A01P3/00A01P1/00
Inventor 王迪
Owner XIAMEN DAKAI BIOTECH CO LTD