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Sugar-free bicarbonate hemodialysis concentrated solution and preparation method thereof

A technology of bicarbonate and hemodialysis, which is applied in the field of hemodialysis, and can solve problems such as the need to improve the balance and safety of the concentrate, high cost of use, and prone to vomiting

Pending Publication Date: 2021-09-10
GUANGZHOU QIJI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide sugar-free bicarbonate hemodialysis concentrate and preparation method thereof, to solve the hemodialysis affecting some personnel proposed in the above background technology, and the use cost is high, and the situation of vomiting is prone to occur. The balance and security needs to be improved

Method used

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  • Sugar-free bicarbonate hemodialysis concentrated solution and preparation method thereof
  • Sugar-free bicarbonate hemodialysis concentrated solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Sugar-free bicarbonate hemodialysis concentrate, including raw materials of the following ingredients:

[0035] Raw material 1: 20 parts of sodium chloride, 1 part of calcium chloride, 1 part of potassium chloride, 0.6 part of magnesium chloride, 1 part of pH regulator, 80 parts of purified water, raw material 2: 6 parts of sodium bicarbonate, 0.5 part of glucose, purified 80 parts of water.

[0036] Further, the pH regulator in the raw material one is sodium diacetate, and the sodium bicarbonate in the raw material two is a solid raw material.

[0037] Further, the ingredients in the second raw material are sodium bicarbonate, glucose and purified water, and the temperature of the purified water is 20 degrees Celsius.

[0038] The preparation method of sugar-free bicarbonate hemodialysis concentrate comprises the following steps:

[0039] S1. Pretreatment: pour hot distilled water into the batching tank, and stir the hot distilled water inside the batching tank to cl...

Embodiment 2

[0047] Sugar-free bicarbonate hemodialysis concentrate, including raw materials of the following ingredients:

[0048] Raw material 1: 20 parts of sodium chloride, 0.9 parts of calcium chloride, 0.5 parts of potassium chloride, 0.3 parts of magnesium chloride, 0.6 parts of pH regulator, 80 parts of purified water, raw material 2: 8 parts of sodium bicarbonate, 0.3 parts of glucose, purified 80 parts of water.

[0049] Further, the pH regulator in the raw material one is glacial acetic acid, and the sodium bicarbonate in the raw material two is a solid raw material.

[0050] Further, the ingredients in the second raw material are sodium bicarbonate, glucose and purified water, and the temperature of the purified water is 10 degrees Celsius.

[0051] The preparation method of sugar-free bicarbonate hemodialysis concentrate comprises the following steps:

[0052] S1. Pretreatment: pour hot distilled water into the batching tank, and stir the hot distilled water inside the batchin...

Embodiment 3

[0060] Sugar-free bicarbonate hemodialysis concentrate, including raw materials of the following ingredients:

[0061] Raw material 1: 20 parts of sodium chloride, 0.9 parts of calcium chloride, 0.5 parts of potassium chloride, 0.3 parts of magnesium chloride, 0.6 parts of pH regulator, 80 parts of purified water, raw material 2: 8 parts of sodium bicarbonate, 0.3 parts of glucose, purified 80 parts of water.

[0062] Further, the pH regulator in the raw material one is glacial acetic acid, and the sodium bicarbonate in the raw material two is a solid raw material.

[0063] Further, the ingredients in the second raw material are sodium bicarbonate and purified water, and the temperature of the purified water is 10 degrees Celsius.

[0064] The preparation method of sugar-free bicarbonate hemodialysis concentrate comprises the following steps:

[0065] S1. Pretreatment: pour hot distilled water into the batching tank, and stir the hot distilled water inside the batching tank ...

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Abstract

The invention relates to the technical field of hemodialysis, in particular to a sugar-free bicarbonate hemodialysis concentrated solution and a preparation method thereof. The sugar-free bicarbonate hemodialysis concentrated solution is prepared from a first raw material including 20 parts of sodium chloride, 0.5-1.5 parts of calcium chloride, 0.3-1 part of potassium chloride, 0.1-0.6 part of magnesium chloride, 0.3-1 part of a PH regulator and 80-100 parts of purified water, and a second raw material including 5-10 parts of sodium bicarbonate, 0.3-0.5 part of glucose and 80-100 parts of purified water. The pH regulator in the raw material I is one of glacial acetic acid and sodium diacetate, the sodium bicarbonate in the raw material II is a solid raw material, and the raw material II comprises one of sodium bicarbonate and purified water or sodium bicarbonate, glucose and purified water. The sugar-free bicarbonate hemodialysis concentrated solution does not contain glucose, so that the concentrated solution is more convenient to store and transport, the occurrence of the deterioration condition of the concentrated solution is reduced, meanwhile, the sugar-free concentrated solution ensures that part of people do not need to take too much sugar, the economic cost can be reduced, and the acidosis correction effect is stronger after the sodium bicarbonate is subjected to the operations such as dissolution and the like.

Description

technical field [0001] The invention relates to the technical field of hemodialysis, in particular to a sugar-free bicarbonate hemodialysis concentrate and a preparation method thereof. Background technique [0002] Hemodialysis is one of the alternative treatment methods for patients with acute and chronic renal failure. It discharges blood from the body to the outside. Through a dialyzer composed of numerous hollow fibers, the concentration of blood and electrolyte solution is similar to that of the human body. The inside and outside of the fiber pass through dispersion, ultrafiltration It is a treatment process in which substances are exchanged using the principles of adsorption, convection, etc., metabolic waste is removed, electrolytes and acid-base balance are maintained, and the purified blood is then reinfused. [0003] Chinese Patent No. CN201711018654.7 provides a hemodialysis solution, including chloride ions, sodium ions, potassium ions, magnesium ions, citrate i...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K47/02A61K47/12A61P7/08A61K33/06
CPCA61K33/14A61K33/06A61K9/0026A61K47/12A61K47/02A61P7/08A61K2300/00
Inventor 黄志贤
Owner GUANGZHOU QIJI BIOTECH CO LTD
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