Eye drops rich in animal and plant active ingredients and preparation method
A technology of active ingredients and eye drops, applied in the field of medicine, can solve the problems that macromolecular drugs are difficult to penetrate the eye, eye tissue immune damage, high treatment risk, etc., so as to nourish the optic nervous system and optic nerve cells, give The drug process is simple and convenient, and the effect of reducing the cost of treatment
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Embodiment 1
[0051] A rich source of animals and plants of the active ingredient of eye drops, wherein the parts comprising the following components by weight: 0.1 parts active polypeptide, 5 parts of herbal extracts, 0.1 parts of lubricating moisturizing enhancer, 0.1 parts of a preservative, a tonicity adjusting agent 1 parts, insulin 0.5mg / mL, the balance made up with saline, pH 6.0.
[0052] The active polypeptide is obtained by the following extraction processes:
[0053] (1) Take a healthy and fresh animal-rich polypeptide animal tissue, tissue liquid or body fluid, debris, cleaning, chopping, tissue mask;
[0054] (2) sodium chloride solution was added an equal mass mixed, colloid milled homogenate was like;
[0055] (3) Add 1 by mass sodium chloride solution and the like mixed, 1% by weight of the starting material proteases (including trypsin, papain, an enzyme complex), the water bath was heated to 50 ℃, the pH adjusted with saturated calcium hydroxide to 7.5 , under constant stirr...
Embodiment 2
[0076] A rich source of plant and animal eye drops the active ingredient, comprising the following parts by weight of component: 5 parts active polypeptide, 15 parts of herbal extracts, moisturizing lubricity enhancers 5 parts, 0.5 parts of a preservative, 5 parts of tonicity adjusting agent, I an amount to make up with saline, pH 8.0.
[0077] The active polypeptide is obtained by the following extraction processes:
[0078] (1) Take a healthy and fresh animal-rich polypeptide animal tissue, tissue liquid or body fluid, debris, cleaning, chopping, tissue mask;
[0079] (2) sodium chloride solution was added an equal mass mixed, colloid milled homogenate was like;
[0080] (3) Add sodium chloride solution three times the mass of the like mixing, adding 2 wt% of the starting protease (including papain, an enzyme complex), the water bath was heated to 55 ℃, saturated with calcium hydroxide adjusted to pH 8.5, constant stirring under hydrolysis 15H;
[0081] (4) placed in a 10 deg.] ...
Embodiment 3
[0101] An eye medium rich in an active ingredient, including the following weight component: 3 parts of the active polypeptide, 10 Chinese medicine extracts, 3 parts of the lubricant moisturizer, 0.3 preservatives, 3 osmotic regulators, The quantity uses physiological saline to make up, pH is 7.0.
[0102] The active polypeptide is obtained by the following extraction processes:
[0103] (1) Take a healthy and fresh animal-rich polypeptide animal tissue, tissue liquid or body fluid, debris, cleaning, chopping, tissue mask;
[0104] (2) Add such weight sodium chloride solution to mix, colloidal grinding is homogenous;
[0105] (3) The addition of 2 times and other sodium chloride solutions are mixed, adding the amount of 1.5% of the weight of the raw material to 52 ° C, the water bath is heated to 52 ° C, and the pH is adjusted to 8.0 with saturated calcium hydroxide to 8.0, stirring at a constant speed, hydrolyzing 12h;
[0106] (4) Placing at 0 ° C for 4 hours, the precipitation ...
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