Synthesis and detection method of modified novel antibacterial resin type pit and fissure sealing agent

A technology of pit and fissure sealing and detection method, which is applied in the clinical field of oral cavity, can solve the problems of insufficient long-term anti-caries performance, local biofilm accumulation, insufficient antibacterial performance, etc., and achieve sustainable antibacterial effect, good mechanical properties and safety, The effect of superior mechanical properties

Pending Publication Date: 2021-09-17
SICHUAN UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0005] Through the above analysis, the existing problems and defects of the prior art are: the resin pit and fissure sealant has polymerization shrinkage, which leads to microleakage and local biofilm accumulation; the existing pit and fissure sealant has insufficient long-term anti-caries performance
[0006] The difficulty in solving the above problems and defects is: how to solve the problem of insufficient antibacterial performance without affecting the polymerization shrinkage and mechanical properties of existing pit and fissure sealants so as to achieve good long-term anti-caries performance

Method used

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  • Synthesis and detection method of modified novel antibacterial resin type pit and fissure sealing agent
  • Synthesis and detection method of modified novel antibacterial resin type pit and fissure sealing agent
  • Synthesis and detection method of modified novel antibacterial resin type pit and fissure sealing agent

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Embodiment Construction

[0055] In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention.

[0056] In view of the problems existing in the prior art, the present invention provides a method for synthesizing and detecting a novel modified antibacterial resin-type pit and fissure sealant. The present invention is described in detail below with reference to the accompanying drawings.

[0057] like figure 1 As shown, the modified novel antibacterial resin-type pit and fissure sealant synthesis and detection method provided by the embodiment of the present invention includes:

[0058] S101: Prepare pit and fissure sealant, and screen the dosage relationship.

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Abstract

The invention belongs to the technical field of oral clinic, and discloses a synthesis and detection method of a modified novel antibacterial resin type pit and fissure sealing agent, which comprises the following steps: preparing the pit and fissure sealing agent, and screening the dosage relation; carrying out performance detection on the prepared pit and fissure sealing agent, grouping according to the mass fraction of DMADDM, and respectively detecting the photocuring depth, cytotoxicity, surface roughness and microhardness of the pit and fissure sealing agent, with five samples in each group; carrying out antibacterial performance detection before and after biological aging; and carrying out micro-leakage detection after biological aging. The modified resin sealant material can effectively resist the aging effect of an oral biofilm, has a long-acting and sustainable antibacterial effect while maintaining excellent mechanical properties, and makes up for the deficiency of the long-acting anti-caries performance of the existing pit and fissure sealant. The quaternary ammonium salt modified pit and fissure sealing agent developed by the invention has a long-acting antibacterial function, can effectively improve the success rate of caries prevention, and is expected to become a clinically ideal novel pit and fissure sealing material.

Description

technical field [0001] The invention belongs to the field of oral clinical technology, in particular to a method for synthesizing and detecting a modified novel antibacterial resin-type pit and fissure sealant. Background technique [0002] At present, dental caries is the oral disease with the highest incidence, and the incidence of dental caries in Chinese children ranks first among children's diseases. The incidence of dental caries in Chinese children is as high as 40% to 70%, of which more than 80% are pit and fissure caries. The unique anatomical and physiological characteristics of the occlusal pits and fissures of children's deciduous molars and young permanent teeth make it difficult to clean food residues and plaques, so the development of caries is very rapid. Pit and fissure sealing technology has been used clinically since 1960. Pit and fissure sealing technology has been recognized as an effective method to prevent pit and fissure caries in primary molars and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/44G01N1/38G01N1/36C12Q1/18G01N33/50
CPCG01N33/442G01N1/38G01N1/36C12Q1/18G01N33/5014G01N2001/364
Inventor 程磊黄禹瑶李好任彪李继遥周学东
Owner SICHUAN UNIV
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