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Preparation method of selenium-rich cell repair liquid

A repair solution and selenium-enriched technology, which is applied in the field of biomedicine, can solve the problems of inability to increase the collagen content of cells and poor cell proliferation ability, and achieve the effects of improving antioxidant capacity, cell survival rate, and removing pesticide residues

Pending Publication Date: 2021-10-08
神究富硒农业发展(山东)有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] (2) Poor ability to proliferate cells;
[0008] (3) Can not increase the collagen content of cells

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1 A kind of preparation method of selenium-enriched cell repair liquid

[0035] Include the following steps:

[0036] (1) Extraction of selenium-rich peptides

[0037] The selenium-enriched soybean meal after oil extraction is crushed, added with a sodium hydroxide solution with a pH of 9 for leaching, and leached at 65° C. for 2 hours at 100 r / min. After the leaching is completed, it is filtered to separate the solid from the liquid, and the solid and leach solution;

[0038] Add hydrochloric acid to the leaching solution, adjust the pH to 4.5, precipitate at 55°C for 2.5 hours, filter after precipitation, and adjust the pH to 7 with sodium hydroxide solution after filtration to obtain a selenium-enriched protein emulsion.

[0039] Add selenium-enriched protein emulsion to protease for enzymolysis. The enzymolysis temperature is 50°C, and the stirring speed is 500r / min for 5h. After the enzymolysis is completed, the temperature is raised to 80°C for inacti...

Embodiment 2

[0064] The selenium content of the selenium-enriched cell repair solution prepared in Example 1 is 2.4 mg / kg;

[0065] After skin abrasions, the selenium-enriched cell repair solution prepared in Example 1 was applied to the skin wounds, twice a day, using 2ml each time, and the healing of the abrasions was observed;

[0066] Using the selenium-enriched cell repair solution prepared in Example 1, the patient's wound recovered, and the recovery time was 10 days.

Embodiment 3

[0068] Select 40 women aged 25-40 and divide them into two groups, 20 people in each group, including 7 people aged 25-30, 7 people aged 30-35, and 6 people aged 35-40 in each group. Apply the selenium-enriched cell repairing liquid prepared in Example 1 on the face every day, once in the morning and once in the evening, each 1ml, and the control group is smearing the cell repairing liquid prepared in Comparative Example 1 on the face every day, once in the morning and evening Once, 1ml each time, after 60 days, observe the improvement of the skin and measure the collagen content of the skin;

[0069] The women in the experimental group who used the selenium-enriched cell repair solution prepared in Example 1 had more rosy skin and better skin gloss than those in the control group, and the collagen content in the skin increased by an average of 12.3% compared with the women in the control group.

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PUM

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Abstract

The invention provides a preparation method of a selenium-rich cell repair liquid. The preparation method comprises the following steps of: extracting selenium-rich polypeptide, and adding materials and stirring. The selenium-rich cell repair liquid prepared by the invention is high in selenium content; the selenium content ranges from 2.3 mg / kg to 2.5 mg / kg; selenium can be supplemented while cells are repaired; the oxidation resistance of the cells is improved; skin scratches can be cured after the selenium-rich cell repair liquid prepared by the invention is used for 9 days to 11 days; the collagen content of the skin can be increased; the collagen content is increased by 12-13% compared with that of a common product after the product is used for 60 days; the cell survival rate can be effectively improved; and the cell survival rate of the selenium-rich cell repair liquid prepared by the invention is improved by 12-13% compared with that of a common product.

Description

technical field [0001] The invention relates to a method for preparing a selenium-enriched cell repair solution, which belongs to the technical field of biomedicine. Background technique [0002] The skin is an important organ of the human body. It plays a role in controlling body temperature, preventing infection and loss of body fluids, immunity and sensing. Extensive damage to the skin may result from trauma, abrasions, skin ulcers, and burns. Damage to the skin is prone to bacterial infection, loss of body fluids and various clinical complications. [0003] The consumption level of wound treatment in our country is far from that of similar foreign products in terms of price. The investment in technology research and development is relatively low, and the product advantages are not obvious, such as the effect is not obvious, the variety is single, there is no series of products, and there is no target customer. Carry out market segmentation, so it is far from meeting th...

Claims

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Application Information

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IPC IPC(8): A61K38/01A61K33/04A61P17/02
CPCA61K38/011A61K33/04A61P17/02A61K2300/00
Inventor 蔡敬海夏晓琳陈红
Owner 神究富硒农业发展(山东)有限公司
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