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Method and system of evaluating a radiation therapy treatment plan

A radiation therapy and treatment planning technology, applied in radiation therapy, treatment, X-ray/γ-ray/particle irradiation therapy, etc., can solve the problem of low cell survival rate

Active Publication Date: 2021-11-19
RAYSEARCH LAB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It is well known that high LET radiation results in lower cell survival per unit absorbed dose than low LET radiation

Method used

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  • Method and system of evaluating a radiation therapy treatment plan
  • Method and system of evaluating a radiation therapy treatment plan
  • Method and system of evaluating a radiation therapy treatment plan

Examples

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Embodiment Construction

[0043] figure 1 A simplified schematic diagram of a computer-based system 100 for generating a radiation therapy treatment plan 114 in accordance with the present invention is shown. The computer-based system 100 includes a memory or database 110 having a radiation therapy treatment plan 114 stored thereon, and a computer program 116 for generating an improved radiation therapy treatment plan 118 . Memory 110 can be any volatile or non-volatile memory device, such as a flash drive, hard drive, optical drive, dynamic random access memory (DRAM), static random access memory (SRAM), and information retrieval and any other suitable equipment for data processing. Additionally, system 100 includes one or more hardware processors 120 capable of accessing memory 110 for performing data processing. The hardware processor 120 can be composed of a central processing unit (CPU), a digital signal processor (DSP), a reduced instruction set computer (RISC), an application specific integrat...

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Abstract

A method of evaluating a radiation therapy (RT) treatment plan for a treatment volume, divided into sub-volumes and having a target volume and one or more organs at risk, OAR. It includes obtaining a RT treatment plan; calculating the linear energy transfer, LET, in each sub-volume; dividing the dose distribution into doses of a first category and a second category in each sub- volume, wherein the first category comprises doses with energy depositions with an LET below a first LET threshold and the second category comprises doses with energy depositions with an LET above a second LET threshold; determining amounts of doses of the first and of the second category in each sub-volume; and performing an analysis of the quality of the RT treatment plan by metrics based on the obtained distribution of doses of the first and of the second category in the target volume and in the OAR.

Description

technical field [0001] The present disclosure relates generally to the field of radiation therapy treatment, and in particular to the generation, optimization and evaluation of radiation therapy treatment plans. Background technique [0002] Cancer is a widespread disease that manifests itself through the erroneous growth of abnormal cells. If the uncontrolled growth of these cells is not stopped, it can be fatal. Globally, the lethal trend of cancer is steadily increasing along with the overall estimated cost of cancer management. This has led to increased public demand for the development of more effective tools and technologies to treat and cure disease. With the rapid development of medical imaging, tumors are diagnosed early when they are still localized or regional. Different types of radiation therapy, brachytherapy, particle therapy and chemotherapy are effective in treating localized cancer cells or tumors. [0003] Radiation therapy is a form of cancer treatmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1031A61N5/1048A61N2005/1087A61N5/1064
Inventor 埃里克·特拉内乌斯
Owner RAYSEARCH LAB