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Absorbable medical surgical suture and preparation method thereof

A technique of surgical thread and absorbing particles, applied in the field of medical materials, can solve the problems of restricting the application of absorbable medical surgical thread, tissue inflammatory response, etc., and achieve the effects of green industrial production, reducing inflammatory response and promoting recovery

Pending Publication Date: 2021-11-23
CHANGCHUN SINOBIOMATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after biodegradable polymer materials are implanted into the body, the degradation fragments, monomers, catalysts, and residual organic solvents in the biodegradable polymer materials may cause tissue inflammation, resulting in tissue damage in the body. Fibrosis and immune response of surrounding tissues, etc.
Especially when absorbable medical surgical thread is used in plastic surgery, due to some adverse reactions of biodegradable polymer materials implanted in the body, the application of absorbable medical surgical thread in the field of cosmetology is greatly limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] An absorbable medical surgical thread is prepared from functional absorbable particles formed of polylactic acid resin with a molecular weight of 70,000 to 100,000 and nano pearl powder with a particle size of 2 to 50 nm.

[0022] A preparation method for absorbable medical surgical thread, comprising the steps of:

[0023] Step 1: use a granulator to knead and granulate nano-pearl powder and polylactic acid resin that account for 2% by mass to make functional polylactic acid resin particles (pearl powder polylactic acid resin particles); After drying, the moisture content of the dried resin particles can meet the requirements of spinning.

[0024] Step 2: Melt the dried functional polylactic acid resin particles through a single-screw melt spinning machine and extrude through the spinneret assembly; transfer the extruded polylactic acid melt to a cooling water tank for cooling treatment at 45°C , to obtain primary fibers for surgical thread; wherein, the temperature o...

Embodiment 2

[0028] An absorbable medical surgical thread is prepared from functional absorbable particles formed of polylactic acid resin with a molecular weight of 70,000 to 100,000 and nano pearl powder with a particle size of 2 to 50 nm.

[0029] A preparation method for absorbable medical surgical thread, comprising the steps of:

[0030] Step 1: use a granulator to knead and granulate nano-pearl powder and polylactic acid resin with a mass ratio of 0.5% to make functional polylactic acid resin particles (pearl powder polylactic acid resin particles); After drying, the moisture content of the dried resin particles can meet the requirements of spinning.

[0031] Step 2: Melt the dried functional polylactic acid resin particles through a single-screw melt spinning machine and extrude through the spinneret assembly; transfer the extruded polylactic acid melt to a cooling water tank for cooling treatment at 40°C , to obtain primary fibers for surgical thread; wherein, the temperature of ...

Embodiment 3

[0035] An absorbable medical surgical thread is prepared from functional absorbable particles formed of polylactic acid resin with a molecular weight of 70,000 to 100,000 and nano pearl powder with a particle size of 2 to 50 nm.

[0036] A preparation method for absorbable medical surgical thread, comprising the steps of:

[0037] Step 1: use a granulator to knead and granulate nano-pearl powder and polylactic acid resin that account for 1% by mass to make functional polylactic acid resin particles (pearl powder polylactic acid resin particles); For drying treatment, the moisture content of the dried resin particles can meet the spinning requirements.

[0038] Step 2: Melt the dried functional polylactic acid resin particles through a single-screw melt spinning machine and extrude through the spinneret assembly; transfer the extruded polylactic acid melt to a cooling water tank for cooling treatment at 40°C , to obtain primary fibers for surgical thread; wherein, the temperat...

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Abstract

The invention discloses an absorbable medical surgical suture and a preparation method thereof. The absorbable medical surgical suture is prepared from functional absorbable particles formed by blending an absorbable high-molecular polymer and nano pearl powder. According to the embodiment of the invention, the nano pearl powder is added into the absorbable medical surgical suture; therefore, the inflammatory reaction of the absorbable high-molecular polymer to tissues in the degradation process can be reduced; furthermore, the effect of the pearl powder can be effectively exerted; thus, the absorbable medical surgical suture has the effect of promoting collagen regeneration; the recovery of tissues around the absorbable medical surgical suture is promoted; and the beautifying effect is achieved.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to an absorbable medical operation thread and a preparation method thereof. Background technique [0002] The traditional absorbable medical surgical thread is catgut prepared from the intestinal mucosa of sheep or cattle. However, after the absorbable medical surgical thread is implanted in the body, it will not only produce a strong biological reaction, but also decompose quickly and have poor absorbability. Stablize. [0003] Biodegradable polymer materials occupy a very important position in the research and development of medical polymer materials. At present, biodegradable polymer materials have been applied in the fields of surgical sutures, bone repair engineering, and drug controlled release. However, after biodegradable polymer materials are implanted into the body, the degradation fragments, monomers, catalysts, and residual organic solvents in the biodegradab...

Claims

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Application Information

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IPC IPC(8): A61L17/08A61L17/12A61L17/14
CPCA61L17/08A61L17/12A61L17/14A61L2400/12A61L2300/30
Inventor 姚丽丽温明哲崔毅
Owner CHANGCHUN SINOBIOMATERIALS
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