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A kind of medicinal composition for treating cough and preparation method thereof
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A composition and drug technology, applied in the field of traditional Chinese medicine, can solve problems such as different medicinal properties
Active Publication Date: 2022-08-09
SICHUAN ACAD OF CHINESE MEDICINE SCI
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[0005] In addition to basic medicines, so far, the number of traditional Chinese medicine compound prescriptions for treating cough reported in the prior art is also very large, but because the prescriptions include many medicinal flavors and different medicinal properties, their scientificity and rationality of medication need to be further studied and standardized.
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Embodiment 1
[0035] Embodiment 1, the preparation of the pharmaceutical composition of the present invention
[0040] For the above six flavors, fritillary fritillary was crushed into coarse powder, extracted with 70% ethanol under reflux for 3 times, each time for 2 hours, the amount of solvent for each time was 5 times the amount of medicinal materials (V / W), filtered, and the filtrate was recovered with ethanol to obtain Extract, standby; medicinal residues and other five flavors such as Anemarrhena are decocted twice with water for 2 hours each time, and the amount of water is 20 times the amount of medicinal materials (20L, V / W), combined with the decoction, filtered, and the filtrate was concentrated to In an appropriate amount, add the above-mentioned Wabu Fritillaria ...
Embodiment 2
[0041] Embodiment 2, the preparation of the pharmaceutical composition of the present invention
[0046] The above six flavors (Wab Fritillaria are broken into coarse grains), add water to decoct twice, 2 hours each time, each time the amount of water is 20 times the amount of medicinal materials (V / W), combine the decoction, filter, and concentrate the filtrate to To a thick paste with a relative density of 1.32-1.35 (60° C.), add 320 g each of sucrose and dextrin, mix well to make granules, and dry to make 1000 g.
Embodiment 3
[0047] Embodiment 3, the preparation of the pharmaceutical composition of the present invention
[0052] The above six flavors (Wab Fritillaria are broken into coarse grains), add water to decoct twice, 2 hours each time, each time the amount of water is 20 times the amount of medicinal materials (V / W), combine the decoction, filter, and concentrate the filtrate to The clear paste with a volume of 800ml, add 1600ml of 95% ethanol, stir well, let stand overnight, filter, recover ethanol from the filtrate under reduced pressure, concentrate to a thick paste with a relative density of 1.32-1.35 (60°C), dry under reduced pressure at 60°C , make dry paste, powder, add 380g each of sucrose and dextrin, mix well, make into granules, dry, make into 1000g, tha...
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Abstract
The invention provides a medicinal composition for relieving cough. 9 parts, 3-9 parts of Campanulaceae, 3-9 parts of licorice. The pharmaceutical composition of the invention has concise medicinal flavor and proper compatibility, and has the functions of moistening the lung, dispersing the lung, clearing the lung, removing phlegm, soothing the throat, clearing away heat and purging fire, clearing away heat and detoxifying, clearing away heat and drying dampness, resolving phlegm and dispelling knots, invigorating spleen and replenishing qi, and the like. It can effectively treat cough, especially wind-heat cough. Its antitussive, expectorant and anti-inflammatory effects are similar to Ermu Powder (the drug pair of Chuan Fritillaria and Anemarrhena), Scutellaria Shegan Decoction (Scutellaria baicalensis). Compared with the three classic formulas of Shegan's medicine pair) and Bellflower Decoction (the medicine pair of Platycodon grandiflorum and licorice), it has significant advantages, and has no obvious toxic and side effects, and has good clinical application value.
Description
technical field [0001] The invention belongs to the field of traditional Chinese medicine, and particularly relates to a medicinal composition for treating cough and a preparation method thereof. Background technique [0002] Cough refers to the six exogenous factors (wind, fire, cold, dampness, summer heat, dryness) or internal injury, which lead to the loss of the lungs, the upward reversal of the lung qi, the impact on the airway, the coughing sound or the expectoration. A disease syndrome, often accompanied by phlegm and inflammation, and most cough medicines, such as some western medicines, often bring unavoidable side effects, and some cough medicines contain poppy shell, codeine and other ingredients, which are addictive. risks of. Currently, there is still a lack of effective and safe drugs for treating cough. [0003] For a long time, Fritillaria is one of the classic Chinese medicines used by Chinese people to treat cough. Because of its good curative effect and ...
Claims
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