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Sampling and detection integrated detection tube structure

A technology for detecting tubes and tube caps, which can be applied to biological material sampling methods, biochemical instruments, and biochemical cleaning devices. It can solve problems such as aerosol infection, sample leakage or overflow, and achieve the effect of reducing biosafety risks.

Pending Publication Date: 2022-03-11
SHENGJING HOSPITAL OF CHINA MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the new crown sample may leak or overflow during the transfer process, aerosol infection may occur when opening the sealed sample tube, mixing samples, pipetting and emptying the sampler, etc.

Method used

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  • Sampling and detection integrated detection tube structure
  • Sampling and detection integrated detection tube structure
  • Sampling and detection integrated detection tube structure

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0027] Specific embodiment one: as Figure 1-2 As shown, the integrated detection tube includes two parts: the detection tube body 10 and the detection tube cover (composed of three parts: the swab storage chamber 20, the chamber cover 40, and the cavity cover anti-drop cap 80); the integrated detection tube as a whole, except for the sealing ring (medical grade silicone), made of medical grade PP material. The internal cavity of the detection tube body 10 is sequentially provided with a lysis area, a cleaning area, and an elution amplification area from top to bottom; the swab storage chamber 20 on the detection tube cover is fixed on the detection tube in the form of screwing. The sealing ring 30 is placed in the groove in the threaded area of ​​the swab storage cavity 20 and the cavity cover 40 to play a role of sealing and anti-pollution. The swab storage chamber 20 is provided with a swab limiting and fixing part 50, which is convenient for fixing and breaking the swab, ...

specific Embodiment 2

[0028] Specific embodiment two: as Figure 3-4 As shown, the shape of the detection tube cover can be varied, and the swab storage chamber on the detection tube cover can be fixed on the detection tube body by means of ultrasonic waves instead of being screwed tightly to the detection tube body. And the chamber cover can be used Figure 3-4 Inner dust cover.

[0029] Specifically, the detection tube cover adopts the corresponding structural design of the sealing ring of the detection tube cover. The tube cover is provided with an inner cavity, and the swab is fixed and extracted through the swab limiter, filter screen and dustproof cap on the detection tube cover. The effects of infiltration, separation, anti-pollution and filtration of impurities.

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PUM

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Abstract

The invention belongs to the technical field of sampling and detection, and particularly relates to a sampling and detection integrated detection tube structure. Integration and automation of processes of sample collection, virus inactivation, nucleic acid extraction, nucleic acid amplification, target sequence detection and the like are realized. Comprising a detection tube body and a detection tube cover. The device is characterized in that the detection tube cover comprises a swab storage cavity and a cavity cover. A swab storage cavity is formed in the top of the detection tube body, a swab limiting and fixing part is arranged in the swab storage cavity, a cavity cover is arranged at the top of the swab storage cavity, and a filter screen is arranged at the bottom of the swab storage cavity and below the limiting and fixing part.

Description

technical field [0001] The invention belongs to the technical field of sampling and detection, and in particular relates to an integrated detection tube structure for sampling and detection. Background technique [0002] Current situation of nucleic acid detection of new coronavirus: nucleic acid detection of new coronavirus mainly takes nasopharyngeal swab / pharyngeal swab samples from subjects for sample pretreatment, nucleic acid extraction, amplification and detection. At present, the nucleic acid detection methods of the new coronavirus mainly include conventional detection methods and rapid detection methods. [0003] Among the routine detection methods for the nucleic acid of the new coronavirus, RT-PCR (reverse transcription polymerase chain reaction) is the most popular in medical units. This method is to first reverse-transcribe the RNA of the new coronavirus into cDNA, and then use the cDNA as a template for PCR amplification. This technology is mature, sensitive ...

Claims

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Application Information

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IPC IPC(8): C12M1/24C12M1/30C12M1/34C12M1/00C12Q1/70C12Q1/6806C12R1/93
CPCC12M23/06C12M23/38C12M33/02C12M37/04C12M41/00C12Q1/70C12Q1/6806C12Q2565/60
Inventor 秦晓松刘勇温文张旖骁
Owner SHENGJING HOSPITAL OF CHINA MEDICAL UNIV
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