Traditional Chinese medicine composition for treating diabetic gangrene

A technology of gangrene and composition, applied in the field of composition, can solve problems such as unsatisfactory effects

Pending Publication Date: 2022-04-05
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the comprehensive treatment effect of western medicine is unsatisfactory, and many patients need amputation

Method used

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  • Traditional Chinese medicine composition for treating diabetic gangrene
  • Traditional Chinese medicine composition for treating diabetic gangrene
  • Traditional Chinese medicine composition for treating diabetic gangrene

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1 granule preparation

[0048] prescription:

[0049]

[0050] Preparation:

[0051] Step A: Distill Nepeta, Fangfeng, Notopterygium, Duhuo, Peucedanum, Rhizoma Chuanxiong, and Citrus aurantium, respectively, to extract volatile oils for later use, and distilled medicinal residues, distilled Chuanxiong, and Citrus aurantii for later use;

[0052] Step B: preparing the distilled aqueous solution of Rhizoma Chuanxiong and Fructus Aurantii obtained in Step A into a 25% ethanol solution for subsequent use;

[0053] Step C: mixing Poria cocos, the distilled Rhizoma Chuanxiong and Citrus aurantii herb residues obtained in step A, percolating and extracting with the ethanol solution obtained in step B, and the percolating liquid is set aside;

[0054] Step D: decoct Bupleurum chinensis, Platycodon grandiflorum, Radix Glycyrrhizae, distilled Schizonepetae, Fangfeng, Notopterygium, Duhuo, and Peucedanum dregs obtained in Step A, decocting twice for 1.5 hours each...

Embodiment 2

[0056] Embodiment 2 Granule preparation

[0057] prescription:

[0058]

[0059] The preparation method is the same as in Example 1.

Embodiment 3

[0060] Embodiment 3 tablet preparation

[0061] prescription:

[0062]

[0063] Preparation:

[0064] Step A: Distill Nepeta, Fangfeng, Notopterygium, Duhuo, Peucedanum, Rhizoma Chuanxiong, and Citrus aurantium, respectively, to extract volatile oils for later use, and distilled medicinal residues, distilled Chuanxiong, and Citrus aurantii for later use;

[0065] Step B: preparing the distilled aqueous solution of Rhizoma Chuanxiong and Fructus Aurantii obtained in Step A into a 15% ethanol solution for subsequent use;

[0066] Step C: mixing Poria cocos, the distilled Rhizoma Chuanxiong and Citrus aurantii herb residues obtained in step A, percolating and extracting with the ethanol solution obtained in step B, and the percolating liquid is set aside;

[0067] Step D: decoct Bupleurum chinensis, Platycodon grandiflorum, Radix Glycyrrhizae, distilled Schizonepetae, Fangfeng, Notopterygium, Duhuo, and Peucedanum dregs obtained in Step A, decocting twice for 1.5 hours each ...

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating diabetic gangrene. The traditional Chinese medicine composition is mainly prepared from notopterygium root, radix angelicae pubescentis, poria cocos, radix saposhnikoviae, herba schizonepetae, ligusticum wallichii, platycodon grandiflorum, radix bupleuri, radix peucedani, fructus aurantii and liquorice. Pharmacological experiments find that the traditional Chinese medicine composition can improve the level of VEGF in serum of diabetic foot model rats, adjust NO and ET balance and reduce the levels of blood lipoprotein a and homocysteine, and the purpose of treating diabetic foot gangrene can be achieved by adjusting vascular related factors of diabetic feet.

Description

technical field [0001] The invention relates to a composition, in particular to a traditional Chinese medicine composition for treating diabetic extremity gangrene, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Diabetes mellitus is a clinical syndrome characterized by chronic hyperglycemia caused by genetic and environmental factors. In the early stage of diabetes, the patient may not have any symptoms except high blood sugar, but if the patient relaxes the treatment or does not treat it at all, the continuous high blood sugar will unknowingly erode the patient's blood vessels and nerves, causing various diseases in the body. Lesions of tissues and organs lead to various serious acute and chronic complications. [0003] Acute complications of diabetes: ketoacidosis and nonketotic hyperosmolar coma are the most common. Acute complications are often menacing, if not treated in time, the mortality rate is very high. [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/16A61P3/10A61P17/02
CPCY02A50/30
Inventor 孙宝雷关永霞程国良
Owner LUNAN PHARMA GROUP CORPORATION
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