Active monitoring and reporting system for drug-induced diseases

A disease and drug source technology, applied in the medical field, can solve problems such as missed ADE intervention opportunities, ADE/ME monitoring system false positives, small sample size of original research data, etc., to achieve the effect of ensuring accuracy and strengthening clinical drug risk management and control

Pending Publication Date: 2022-04-05
SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The current ADE / ME monitoring system has problems such as false positives, missed negatives, low reporting rate, low reporting accuracy, and inconsistent evaluation standards for the correlation between suspicious drugs and adverse events, so it cannot reflect the true occurrence level of ADE or ME. This further resulted in the small sample size, low sample quality and poor timeliness of the raw data of adverse drug event research, which brought inconvenience to clinical drug safety supervision and drug quality feedback
[0005] 2. Some ADE / ME can be avoided or discovered at an early stage, but the current ADE / ME monitoring system is mostly for post-event treatment and lacks an early warning mechanism. The lack of early warning makes clinical treatment miss the best time to intervene in ADE, increasing the Incidence and severity of ADEs
[0006] 3. ADE reporting requires accuracy and needs a certain amount of time to be evidence-based, while ADE early warning requires timeliness and early warning of potential ADE risks. The current ADE / ME monitoring system is difficult to simultaneously meet the requirements of accurate reporting and timely early warning

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Active monitoring and reporting system for drug-induced diseases
  • Active monitoring and reporting system for drug-induced diseases
  • Active monitoring and reporting system for drug-induced diseases

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0112] Example 1: For patients over 65 years old with a history of falls or fractures, the drugs on the high-risk drug list include: midazolam, diazepam, alprazolam, diazepam, nitrazepam, and clonazepam , lorazepam, sulpiride, flupenthixol, melitracen, risperidone, clozapine, droperidol.

[0113] Drugs in the list of contraindicated drugs include: sulpiride, flupenthixol, melitracen, risperidone, clozapine, droperidol. The above list can be sent to the patient's physician in charge to remind the risks of medication.

example 2

[0114] Example 2: When the patient in Example 1 has new symptoms of heart failure, the newly added drugs in the banned drug list for the patient should include: cilostazol and non-steroidal anti-inflammatory drugs.

[0115] Compared with the prior art, the beneficial effect of the present invention is that the patient medication risk prompt module can output the latest prohibited drug list and high-risk medication list based on the patient's real-time physical condition, and send them to the competent physician and pharmacist in the form of a list of precautions for medication. Clinical medication provides accurate and timely reference, forming the first level of risk prevention and control beforehand.

[0116] The medication error monitoring module is used to judge whether the patient's current medication is wrong. Preferably, for the medicine currently used by the patient, it is judged whether the medicine belongs to the contraindicated medicine of the patient according to t...

example 3

[0119] Example 3: Adverse events in the adverse event set of ibuprofen include: liver injury, parameters of adverse events related to liver injury include: (1) ALT>40U / L (upper limit of normal value), TB>1×ULN ( Upper limit of normal value), (2) ALT>2×ULN (2 times upper limit of normal value) in a single test, TB>2×ULN (upper limit of normal value). The ADE / ME intervention parameters of ibuprofen-induced liver injury include: (1) discontinuation or reduction of ibuprofen, (2) glutathione, tiopronin, glycyrrhizic acid preparations, polyene phosphorylcholine apply.

[0120] The medication process monitoring and early warning module includes: (1) hierarchical early warning sub-module, which is used to output different levels of early warnings for monitored suspected adverse drug events, upcoming medication errors, and medication errors that have occurred. (2) The doctor's order medication monitoring sub-module, which is used to check the medication errors when the doctor's order...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to an active monitoring and reporting system for drug-induced diseases, which is used for monitoring clinical treatment process information of a patient, performing graded early warning on adverse drug events and drug use errors, performing active reporting, outputting graded early warning according to the risk degree after drug use risk information is monitored, and meanwhile, performing graded early warning according to the treatment process information of the patient. According to the method and the system, the adverse drug events are actively reported after the relevance between the adverse reactions and the suspicious drugs is determined, so that the drug use risk is effectively prevented, and the reporting rate and the reporting accuracy of the adverse events are improved.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to an active monitoring and reporting system for drug-induced diseases. Background technique [0002] Adverse drug events (ADEs) and medication errors (ME) are one of the main causes of drug-induced diseases. Important measures of institutional adverse event rates. The current main ADE monitoring methods include adverse event medical record review method and voluntary reporting system method. The occurrence of ADE is collected through medical record review and voluntary reporting. The number and quality of reports and signal detection capabilities of this method depend on medical institutions. Reporting awareness and cooperation, there are problems such as false positives, missed negatives, and post-event reporting, which cannot reflect the true occurrence level of ADE or ME, and the current ADE monitoring is "post-event" passive monitoring, lacking in advance prevention. [0003...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G16H10/60G16H15/00G16H40/20G16H50/30G16H70/40
Inventor 边原李炼吴丽韩丽珠尹琪楠雷洋罗尧郑星月吴行伟童荣生龙恩武闫峻峰杨勇舒永全何林
Owner SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap