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Pharmaceutical composition for treating knee osteoarthritis as well as preparation method and use method thereof

A technology for knee osteoarthritis and composition, applied in the field of pharmaceutical composition for treating knee osteoarthritis and its preparation, to achieve the effect of reducing inflammation and promoting cellular immunity

Active Publication Date: 2022-04-15
北京市东城区和平里社区卫生服务中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing studies on external treatment of traditional Chinese medicine mostly focus on the overall syndrome differentiation, from promoting blood circulation to removing blood stasis, expelling wind and removing dampness, and lack of syndrome differentiation treatment for local lesions (wind, phlegm, blood stasis, collaterals, etc.), especially for local phlegm and blood stasis lesions. treat

Method used

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  • Pharmaceutical composition for treating knee osteoarthritis as well as preparation method and use method thereof
  • Pharmaceutical composition for treating knee osteoarthritis as well as preparation method and use method thereof
  • Pharmaceutical composition for treating knee osteoarthritis as well as preparation method and use method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Prepare the pharmaceutical composition according to the following proportioning:

[0020] Inula 15g, Trichosanthes 15g, fried mustard seeds 6g, clematis 9g, osmanthus 9g, safflower 15g, sumac 9g, angelica 15g, salvia miltiorrhiza 15g, raw Eucommia 15g, fried aurantium 9g, roasted licorice 6g.

[0021] The preparation process is as follows:

[0022] A. Weigh the raw materials according to the above weight, add 897ml of water to the above raw materials for the first decoction, and soak for 30 minutes;

[0023] B. Put the soaked medicine and water into the decoction pot, boil on high heat, boil on low heat for 30min, and filter out the medicine liquid.

[0024] C. After filtering out the medicinal liquid, add 783ml of water to the raw materials again, boil with high heat, simmer for 30 minutes on low heat, and filter out the medicinal liquid.

[0025] D. Take the two filtered medicinal liquids, mix them, and pack them in 100ml.

[0026] Take the above-mentioned medicina...

Embodiment 2

[0028] Prepare the pharmaceutical composition according to the following proportioning:

[0029] Inula 30g, Trichosanthes 30g, fried mustard seeds 9g, clematis 15g, cinnamon sticks 12g, safflower 30g, sumac 15g, angelica 30g, salvia miltiorrhiza 30g, raw Eucommia 15g, fried aurantium 15g, roasted licorice 6g.

[0030] The preparation process is as follows:

[0031] A. Weigh the raw materials according to the above weight, add 1540ml of water to the above raw materials for the first decoction, and soak for 60 minutes;

[0032] B. Put the soaked medicine and water into the decocting pot, boil on high heat, boil on low heat for 60min, and filter out the medicine liquid.

[0033] C. After filtering out the liquid medicine, re-add 830ml of water to the raw materials, boil with high heat, simmer for 40 minutes on low heat, and filter out the liquid medicine.

[0034] D. Take the two filtered medicinal liquids, mix them, and pack them in 100ml.

Embodiment 3

[0036] Prepare the pharmaceutical composition according to the following proportioning:

[0037] Inula 20g, Trichosanthes 20g, fried mustard seeds 8g, clematis 20g, osmanthus 30g, safflower 20g, sumac 12g, angelica 20g, salvia miltiorrhiza 20g, raw Eucommia 18g, fried aurantium 18g, roasted licorice 9g.

[0038] The preparation process is as follows:

[0039] A. Weigh the raw materials according to the above weight, add 1398ml of water to the above raw materials for the first decoction, and soak for 40 minutes;

[0040] B. Put the soaked medicine and water into the decoction pot, boil on high heat, boil on low heat for 50min, and filter out the medicine liquid.

[0041] C. After filtering out the medicinal liquid, add 752ml of water to the raw material again, boil with high heat, simmer for 35 minutes on low heat, and filter out the medicinal liquid.

[0042] D. Take the two filtered medicinal liquids, mix them, and pack them in 100ml.

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Abstract

The invention relates to a pharmaceutical composition for treating knee osteoarthritis and a use method thereof. The traditional Chinese medicine is characterized by being prepared from the following raw materials in parts by weight: 15-30g of inula flower, 15-30g of trichosanthes kirilowii maxim, 6-12g of fried mustard seed, 9-30g of radix clematidis, 9-30g of cassia twig, 15-30g of safflower, 9-15g of sappan wood, 15-30g of angelica sinensis, 15-30g of salvia miltiorrhiza, 15-30g of raw eucommia ulmoides, 9-30g of fried immature bitter orange and 6-9g of honey-fried licorice root. The invention further provides a medicine for treating knee osteoarthritis, and the medicine composition provided by the invention is a traditional Chinese medicine formula, has small toxic and side effects, and can obviously reduce the pain and stiffness degree of knee osteoarthritis.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating knee osteoarthritis and a preparation method and application method thereof. Background technique [0002] Knee osteoarthritis (KOA) is a chronic degenerative joint disease, clinically manifested mainly by knee joint pain, limited mobility, and joint deformity, which may be related to age, gender, occupation, race, obesity, Strain, endocrine and metabolic abnormalities, environmental factors and other factors are related. With the acceleration of the aging process of society, the incidence of KOA is increasing year by year. At present, oral non-steroidal anti-inflammatory drugs are mainly used for pain relief and topical drugs to relieve symptoms and delay the progress of the disease. External treatment of traditional Chinese medicine is an effective characteristic therapy, which has the advantages of good curative effect, le...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/08A61P19/02A61K41/00
CPCY02A50/30
Inventor 周源田瑶李云张若竹
Owner 北京市东城区和平里社区卫生服务中心
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