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Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense

A dual-continuous phase and extraction technology, which is applied in the fields of process efficiency improvement, pharmaceutical formulations, essential oils/fragrances, etc., can solve problems such as low extraction efficiency, large loss of non-water-soluble components, and increased production costs, so as to achieve improved extraction Efficiency, high extraction rate, guaranteed extraction effect

Pending Publication Date: 2022-05-24
上海澄穆化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The extraction efficiency of the above extraction method is low, and the components in the extract are mainly water-soluble components, a small amount of fat-soluble and volatile oils, the loss of non-water-soluble components in the material is relatively large, and impurities are easy to produce, which is not conducive to the purification of products
[0007] Therefore, some enterprises also use steam distillation-ethanol continuous extraction method for extraction. Although this method can effectively extract the active ingredients in frankincense, the extraction steps are too complicated and the energy consumption is high, which greatly increases the production cost of the enterprise. conducive to actual production

Method used

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  • Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense
  • Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense
  • Bicontinuous phase extracting solution, preparation method thereof and extraction method applied to frankincense

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-6

[0058] A dual-continuous phase extract, the components and their corresponding parts by weight are shown in Table 1, and prepared by the following steps: A1, first raise the temperature of phase A to 80-85°C, and heat up phase A at 400r / min Stir for 20min; heat up phase B to 80-85°C, and stir at 400r / min for 5min;

[0059] Wherein, the polyhydric alcohol in phase A is 1,3-butanediol;

[0060] The polyglycerols in phase B are composed of polyglycerol-5 trioleate and polyglycerol-10 diisostearate in a weight ratio of 4:1; alkanes are C 12-19 Alkanes; ester oil is triglyceride (ethylhexanoate);

[0061] A2. Mix phase B and phase A again, and stir at 1300r / min for 3min to obtain AB mixed phase;

[0062] A3. Finally, lower the temperature of the mixed phase AB to 50-60°C, add phase C, and stir at 400r / min for 5 minutes to obtain a bicontinuous phase extract; the vegetable oil in phase C is white pond flower seed oil.

[0063] Each component and its weight (kg) in table 1 embodim...

Embodiment 7

[0068] A double continuous phase extract, except that the polyhydric alcohol in phase A is glycerol, the others are the same as in Example 1.

Embodiment 8

[0070] A dual-continuous phase extraction solution, except that the polyol in phase A is composed of 1,3-butanediol and dipropylene glycol in a weight ratio of 1:1, and the others are the same as in Example 1.

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Abstract

The invention relates to the field of preparation of compounds, in particular to a bicontinuous phase extracting solution, a preparation method of the bicontinuous phase extracting solution and an extraction method applied to frankincense. The bicontinuous phase extracting solution is prepared from the following components in parts by weight: 20 to 25 parts of deionized water; 32 to 45 parts of polyol; 12 to 25 parts of polyglycerol; 2 to 10 parts of alkanes; 2 to 10 parts of ester grease; and 1-5 parts of vegetable fat. According to the present invention, when the obtained bicontinuous phase extraction liquid is applied to frankincense extraction, the extraction efficiency can be ensured, the effective components in frankincense can be effectively retained, and the extracted frankincense maximally contains 3.526% (35.26 g / 1000 g) of octyl acetate, 28.63% (286.3 g / 1000 g) of triterpenoid total organic acid and 16.26% (162.6 g / 1000 g) of total polysaccharide.

Description

technical field [0001] The application relates to the field of medicine extraction and its preparation, more specifically, it relates to a bicontinuous phase extraction solution, its preparation method and its application to frankincense extract. Background technique [0002] Frankincense, the resin exuded from the bark of Boswellia carterii Birdw. and Boswellia bhaw-dajiana Birdw., a plant of the genus Boswellia in the olive family, is a herbal medicine with broad development prospects. Studies have found that frankincense extract has pharmacological effects such as promoting blood circulation, relieving pain, reducing swelling, promoting muscle growth, anti-inflammation, anti-tumor, anti-oxidation, and lowering blood sugar. Therefore, how to efficiently extract frankincense has become a major research topic at this stage. [0003] It is known that the main active ingredients of frankincense include pentacyclic triterpenes, tetracyclic triterpenes, macrocyclic diterpenes, p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C11B9/02A61K36/324
CPCC11B9/025A61K36/324Y02P10/20
Inventor 杨凯辛英祥孙学磊
Owner 上海澄穆化妆品有限公司
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