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Anti-aging composition as well as preparation method and application thereof

A composition and anti-aging technology, applied in the field of anti-aging composition, anti-aging composition and preparation, can solve the problems of difficult biological effects of active ingredients, slow anti-wrinkle response, insignificant effect, etc., to reduce melanin deposition, delay Effects of skin aging, resistance to external aggressions and free radicals

Pending Publication Date: 2022-06-17
COCOCHI BIOTECHNOLOGY (HANGZHOU) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there are anti-aging cosmetics or anti-wrinkle cosmetics used on the skin surface on the market, but there are some defects and problems in practical application. , the anti-wrinkle response is relatively slow, the effect is not significant, etc.

Method used

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  • Anti-aging composition as well as preparation method and application thereof
  • Anti-aging composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0048] This embodiment provides an anti-aging composition, comprising nanoliposomes and active components loaded on the nanoliposomes, and the anti-aging composition includes by weight: 0.011% diglucosyl gallic acid , 0.5% glucosyl hesperidin, 0.0447% spilanthol extract, 0.0001% biotin, 0.0001% caffeine, 1.8% cholesterol, 1.2% behenyl alcohol, 6.3% hydrogenated lecithin, the balance is deionized water .

[0049] The preparation method of the anti-aging composition comprises the following steps:

[0050] a) Dissolve diglucosyl gallic acid, glucosyl hesperidin, spilanthol extract, biotin, caffeine, cholesterol, behenyl alcohol and hydrogenated lecithin in absolute ethanol in proportion to obtain a mixed solution ;

[0051] b) Evaporating and removing the absolute ethanol in the mixed solution of step a), adding deionized water at 40° C., ultrasonically treating for 15 min, and the ultrasonic frequency being 15 Hz; after the ultrasonic treatment is completed, filter to obtain t...

Embodiment 2

[0053] This embodiment provides an anti-aging composition, including nano-liposomes and active components loaded on the nano-liposomes, and the anti-aging composition includes by weight: 1.1% diglucosyl gallic acid , 1.5% glucosyl hesperidin, 0.8% spilanthol extract, 0.0005% biotin, 0.0005% caffeine, 2.6% cholesterol, 1.5% behenyl alcohol, 6.5% hydrogenated lecithin, the balance is deionized water .

[0054] The preparation method of the anti-aging composition comprises the following steps:

[0055] a) dissolving diglucosyl gallic acid, glucosyl hesperidin, spilanthol extract, biotin, caffeine, cholesterol, behenyl alcohol and hydrogenated lecithin in absolute ethanol in proportion to obtain a mixed solution;

[0056] b) Evaporating and removing the absolute ethanol in the mixed solution of step a), adding deionized water at 50° C., and ultrasonically treating for 18 minutes at a frequency of 25 Hz; after the ultrasonic treatment is completed, filter to obtain an anti-aging c...

Embodiment 3

[0058] This embodiment provides an anti-aging composition, comprising nanoliposomes and active components loaded on the nanoliposomes, and the anti-aging composition includes by weight: 0.011% diglucosyl gallic acid , 0.01% glucosyl hesperidin, 0.01% spilanthol extract, 0.00001% biotin, 0.00001% caffeine, 0.6% cholesterol, 0.1% behenyl alcohol, 6% hydrogenated lecithin, the balance is deionized water .

[0059] The preparation method of the anti-aging composition comprises the following steps:

[0060] a) dissolving diglucosyl gallic acid, glucosyl hesperidin, spilanthol extract, biotin, caffeine, cholesterol, behenyl alcohol and hydrogenated lecithin in absolute ethanol in proportion to obtain a mixed solution;

[0061] b) Evaporate and remove the absolute ethanol in the mixed solution of step a), add deionized water at 60° C., ultrasonically treat for 15-20min, and the ultrasonic frequency is 15-35Hz; after the ultrasonic treatment is completed, filter to obtain the anti-ag...

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Abstract

The invention discloses an anti-aging composition as well as a preparation method and application thereof, the anti-aging composition comprises nano-liposome and active components loaded on the nano-liposome, and the active components comprise diglucosyl gallic acid, glucosyl hesperidin, a chrysanthemum extract, biotin and caffeine, the invention further discloses application of the anti-aging composition in preparation of cosmetics. The anti-aging composition can promote proliferation of human skin fibroblast cells, promote generation of collagen and improve the transdermal absorption capacity of the anti-aging composition, so that wrinkles are improved, the skin color is improved, damaged skin is repaired, and dry skin is improved.

Description

technical field [0001] The invention belongs to the field of cosmetics, and relates to an anti-aging composition, in particular to an anti-aging composition and a preparation method and application thereof. Background technique [0002] The tissues and cells of the epidermal layer of human skin can not only protect the human body from external aggression through the epidermal barrier, but also play a role in delaying the aging of skin tissue through the water retention or moisturizing mechanism that prevents the evaporation of water in the skin tissue. The functions of the barrier construction of the skin epidermis and the moisturizing and anti-aging of the skin epidermis are both crucial and indispensable for the survival of the body and the protection of the tissue. Skin tissue cells, like other cell types in the human body, will age and decline in structure, formulation, and function over time and with the aging of the body, and many metabolic wastes and inactivation, agi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/60A61K8/67A61K8/49A61K8/14A61Q19/00A61Q19/08
CPCA61K8/9789A61K8/60A61K8/602A61K8/673A61K8/4953A61K8/14A61Q19/00A61Q19/08A61Q19/005A61Q19/007A61K2800/782A61K2800/5922A61K2800/412A61K2800/82Y02P20/54
Inventor 川崎清刘丽陆宗奇陈宏磊
Owner COCOCHI BIOTECHNOLOGY (HANGZHOU) CO LTD