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Application of radix pseudostellariae rootlet extract as avian paramyxovirus type 1 vaccine adjuvant

A technology of virus vaccines and extracts, which is applied in the field of application of Pseudostellariae Radix as an adjuvant for poultry type 1 paramyxovirus vaccine, can solve the problems that have not yet been reported on the application of Pseudostellaria heteromyxovirus, and achieve the goal of avian paramyxovirus type 1 The effect of antibody level promotion

Pending Publication Date: 2022-07-05
FUJIAN BRADY PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no report on the application of Pseudostellaria ginseng on waterfowl

Method used

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  • Application of radix pseudostellariae rootlet extract as avian paramyxovirus type 1 vaccine adjuvant
  • Application of radix pseudostellariae rootlet extract as avian paramyxovirus type 1 vaccine adjuvant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0026] Experiment on the effect of the extract of Radix Radix officinalis on the antibody level of avian paramyxovirus type 1 vaccine

[0027] 1 Materials and methods

[0028] 1.1 Materials

[0029] The 1-day-old healthy Muscovy duck was purchased from a poultry company in Putian, and the antibody of avian type 1 paramyxovirus was negative after the serum collection; The virus FP1 / 02 strain was inactivated and prepared into an oil emulsion vaccine.

[0030] Radix Radix Ginseng extract dry powder: according to the preparation method disclosed in Example 1 of Chinese Patent CN 201610758305.8, the Radix Ginseng Radix Extract is obtained, adding 6% soluble starch to the Radix Ginseng Radix Extract in g / mL, stirring and mixing, Then spray-drying was carried out to obtain the dry powder of Radix Ginseng Radix Extract.

[0031] 1.2 Methods

[0032] 1.2.1 Animal grouping

[0033] 270 1-day-old healthy Muscovy ducks were raised on the Internet according to conventional feeding met...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine application, and particularly discloses application of a radix pseudostellariae rootlet extract as an avian paramyxovirus type 1 vaccine adjuvant. It is found for the first time that the radix pseudostellariae rootlet extract has a remarkable promoting effect on the avian paramyxovirus type 1 antibody level, and a theoretical basis is provided for development of radix pseudostellariae rootlets as an avian paramyxovirus type 1 vaccine adjuvant.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine applications, and in particular relates to the application of an extract of Radix Radix officinalis as an adjuvant for avian type 1 Paramyxovirus vaccine. Background technique [0002] Taizishen is the dried root tuber of Caryophyllaceae, rich in amino acids, polysaccharides, saponins, cyclic peptides, flavonoids and volatiles. It has the functions of lowering blood sugar, antioxidant, anti-dermatitis, enhancing immunity and improving lung function. The basic substance of Radix Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma is the same as that of Radix Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma root, the biomass of Radix Rhizoma Radix Rhizoma root is about 14.93% of the dry weight of Radix Rhizoma Radix Rhizoma root, but the total amount of ginse...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/39A61K39/155A61P31/14A61P37/04
CPCA61K39/39A61K39/12A61P31/14A61P37/04A61K2039/55588C12N2760/18034
Inventor 张炎达潘慧青赵齐林贺桂
Owner FUJIAN BRADY PHARMA CO LTD
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