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Drug-loaded cutting balloon catheter

A technology for cutting balloon catheters and drug loading, which is applied in balloon catheters, medical science, surgery, etc., can solve the problem of increased filling and fitting time of distal myocardial ischemia and necrosis, poor filling time drug treatment effect, and increased balloon pressure. The risk of accidental rupture of the capsule can increase the drug loading efficiency, reduce the loss of the drug, and reduce the irradiation time.

Pending Publication Date: 2022-07-29
WEST CHINA HOSPITAL SICHUAN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, when the conventional drug-coated balloon is delivered to the target lesion site, repeated "filling-withdrawing-filling-withdrawing" operations are required to complete the release of the drug. For elderly patients, too long filling and fitting time will increase the risk of distal myocardial ischemic necrosis, and too short filling time will make the drug treatment effect poor. The complexity of the doctor's operation, and it will increase the risk of accidental rupture of the balloon

Method used

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  • Drug-loaded cutting balloon catheter
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  • Drug-loaded cutting balloon catheter

Examples

Experimental program
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Effect test

Embodiment 1

[0062] At present, when the drug-coated balloon is used, when the balloon is inflated, it will adhere to the inner wall of the blood vessel at the lesion and block the blood flow there. If the blood flow is blocked for a long time, it will cause local myocardial ischemia, which will affect the human body. Form greater harm and bring serious side effects. Therefore, the recommended time for balloon dilation in clinical practice will be controlled at 30 seconds or less, so repeated filling and retraction operations are required, which not only increases the operation time, but also increases the operation risk during the operation. In order to solve the problems existing in the current prior art, the present embodiment 1 provides a drug-loaded cutting balloon catheter, refer to Figure 1-Figure 5 In a preferred embodiment, the drug-loaded cutting balloon catheter includes an inner tube 8 , an outer tube 9 , a balloon 2 , a developing ring 3 , a hypotube 12 and a catheter holder ...

Embodiment 2

[0074] refer to Figure 6-Figure 9 , this embodiment provides a preferred structure of the drug-loaded cutting balloon catheter.

[0075] In this embodiment, the balloon catheter includes an inner tube 8, an outer tube 9, a balloon 2, a developing ring 3, a hypotube 12 and a catheter holder 14. The difference from the structure disclosed in Embodiment 1 is that this embodiment The balloon catheter in the example is no longer provided with the perfusion channel 10 .

[0076] In a preferred embodiment, the outer surface of the balloon 2 is provided with 3-10 spinous processes 4 in the circumferential direction, the height of the spinous processes 4 is 0.2-1.0 mm, and a hollow groove is provided at the bottom of the spinous process 4, There is a hollow microtube 6 in it, and the inner diameter of the hollow microtube 6 allows at least a single red blood cell to pass through, so as to meet the blood supply and oxygen supply at the far end of the myocardium; The inner diameter is...

Embodiment 3

[0082] refer to Figure 10-Figure 13 , this embodiment provides a preferred structure of the drug-loaded cutting balloon catheter.

[0083] In this embodiment, the balloon catheter includes an inner tube 8 , an outer tube 9 , a balloon 2 , a developing ring 3 , a hypotube 12 and a catheter holder 14 , the balloon 2 is provided with a perfusion channel 10 , and the bottom of the spinous process 4 is The hollow microtube 6 is provided, the setting of the perfusion channel 10 is the same as that in the above-mentioned embodiment 1, and the specific setting of the hollow micro-pipe 6 is the same as that in the above-mentioned embodiment 2.

[0084]Preferably, the perfusion channels 10 are distributed between the spinous processes 4 at intervals, and the number and size of the perfusion channels 10 and the hollow microtubes 6 at the bottom of the spinous processes 4 can be selected and set according to actual needs. In a more preferred embodiment, since patients have different age...

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Abstract

The invention relates to a medicine-carrying cutting balloon catheter which comprises a balloon capable of being filled, the outer surface of the balloon is coated with medicine, the balloon is provided with a plurality of axial spinous processes, and blood can still pass through the balloon even after the balloon is filled and expanded by arranging an axially-through perfusion channel in the balloon or arranging a hollow microtube below the spinous processes. The balloon can have sufficient time to be attached to a blood vessel for drug release, repeated filling and withdrawing operation on the balloon is not needed, drug loss is reduced, operation efficiency is improved, and irradiation time of a doctor and a patient is shortened.

Description

technical field [0001] The invention relates to the field of interventional medical instruments, in particular to a cutting balloon catheter loaded with medicine. Background technique [0002] Percutaneous coronary intervention (percutaneous coronary intervention, PCI) refers to the treatment of improving myocardial blood perfusion by dredging stenotic or even occluded coronary lumen through cardiac catheterization. Its technical classification mainly includes percutaneous coronary balloon angioplasty, coronary stenting, coronary atherectomy, cutting balloon into the line and intracoronary thrombus aspiration and so on. Among them, coronary stent implantation is the most classic interventional treatment method, and once the stent is implanted in the body, it will remain in the blood vessel forever. Although the technology is very mature and very safe, there are still long-term in-stent restenosis and Risk of stent thrombosis. [0003] Drug-coated Balloon (DCB) is a cathete...

Claims

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Application Information

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IPC IPC(8): A61M25/10A61B17/22
CPCA61M25/1002A61M25/1011A61M25/104A61M25/10183A61B17/22A61M2025/105A61M2025/109A61M2025/1079A61B2017/22001A61B2017/22067A61B2017/22081
Inventor 冯沅陈茂徐亚鹏杨夏燕虞奇峰
Owner WEST CHINA HOSPITAL SICHUAN UNIV
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