Chinese medicinal compound preparation for treating liver fibrillation disease and its preparation method

Abstract

The invention discloses a compound preparation for curing liver fibrosis, adopting the following raw materials or the extraction of the alcohol-water or the water of the raw materials as the active compotents to make it: densen 416-936g, Radix astragali 277-624g, Schisandra chinensis 277-624g, red chinese harbaceous peony 277-624g, root of herbaceous peony 138-312g, fruit of glossy privet 277-624g, lesser hypericum 277-624g, eclipta prostrata 138-312g, and licorice root 138-312g. Mix the rough powder of each raw material to make one or multiple combination bodies, use alcohol-water or water to heat-back flow or filter, to obtain one or multiple extract liquids as the active componentsI-VIII, and mix the active component directly or mix multiple active components evenly to make into the needed drug forms.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating liver fibrosis, including the composition of the traditional Chinese medicine preparation and a preparation method thereof. Background technique [0002] Liver fibrosis is an inevitable pathological process for most chronic liver diseases to develop into liver cirrhosis and primary hepatocellular carcinoma, and is the pathological basis of many chronic liver diseases. Hepatic fibrosis is mainly caused by intrahepatic inflammation caused by various etiologies, resulting in hyperplasia of fibrous connective tissue in the liver, which is manifested as an increase in collagen content and excessive deposition in liver tissue. According to statistics, the incidence of liver fibrosis in mild hepatitis is 64%, and the incidence of liver fibrosis in moderate and severe hepatitis is 100%. Professor Hans. who will cure the vast majority of chronic liver diseases in the worl...

AI Technical Summary

Problems solved by technology

[0003] At present, drugs that are put into clinical use or trials, such as hormones (corticosteroids), malotilate (diisopropyl-1,3-diethylthio-2-malonate), r-interferon (Gamma-lnterferon, Lfn-r), colchicine (colchicine), etc., one is that the toxic and side effects are large, and the other is that the price is high and the curative effect is not accurate

It is imperative to develop corresponding anti-hepatic fibrosis traditional Chinese medicine preparations, including traditional prescriptions, such as Guizhi Fuling Pills, etc., and innovative compound prescriptions, such as Compound Biejiaruangan Tablets; there are single herbal preparations, such as Danshen injection, etc. also have active ingredients and components, such as total glucosides of paeony, curcumone, tetrandrine, etc., the research on the above-mentioned traditional Chinese medicines against liver fibrosis has the following problems: 1. Can not take into account the traditional Chinese medicine itself characteristics, completely applying and copying some modern research methods, thus failing to effectively discover traditional medicine; 2. Lack of rigorous scientific research design, which affects the credibility of the results; 3. Cannot be effectively digested and absorbed; 4. Failed to carry out development research in strict accordance with the technical requirements stipulated in the New Drug Approval Measures, resulting in inability to deepen research and commercialize