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Medicine for treating chronic kidney failure and its preparing process

A chronic renal failure and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of lack of effective prevention and treatment methods, poor curative effect, damage to nephrons, etc.

Inactive Publication Date: 2006-09-20
NAT ENG RES CENT FOR MODERNIZATION OF TRADITIONAL CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many drugs for the treatment of kidney disease, their efficacy is not good
Therefore, there is still a lack of effective prevention and treatment methods for the progressive damage of residual nephrons caused by various reasons, leading to chronic renal failure.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: take by weighing raw material by following proportioning, weight is in kilograms:

[0036] Chuanxiong 25 Astragalus 50 Rhubarb 18.75 Angelica 25 Epimedium 18.75

[0037] Habitat 25, Paeoniae Alba 18.75, Alisma 18.75, Poria 18.75 Sanqi 7.5

[0038] Crush the above-mentioned raw materials except Panax notoginseng; reflux extraction with 50% ethanol for 3 times, each time for 1.5 hours, the first ethanol dosage is 600,000 ml, and the second and third ethanol dosages are 400,000 ml respectively; combined extraction Liquid, concentrated to a thick paste, add 3 kg of starch and mix evenly, put it on a plate for drying, collect the dry extract and powder; then add raw Sanqi powder and an appropriate amount of starch and mix evenly, and the appropriate amount of starch refers to the weight of the finished medicine after the starch is added to 9 kg; use 80% ethanol as a binder, granulate with a 16-mesh sieve; dry at a low temperature below 60°C; after granulation ...

Embodiment 2

[0039] Embodiment 2: Pulverize other raw materials except Radix Notoginseng according to the weight proportion of Example 2 in Table 3; reflux extraction with 50% ethanol for 3 times, each 1.5 hours; the ethanol consumption meets the following proportioning, and the weight is in kilograms Gauge, volume in liters:

[0040] First time: weight of crude drug: volume of ethanol = 1: 2.5~3

[0041] The second time: the weight of the crude drug: the volume of ethanol = 1: 1.5 ~ 2

[0042] The third time is the same as the second time.

[0043] Combine the extracts, concentrate to a thick paste, add 1 to 1.5% starch by weight and mix evenly, dry, collect the dry extract and powder; then add raw Sanqi powder and appropriate amount of starch and mix evenly, the appropriate amount of starch It means that the weight of the finished medicine after starch is added is 4-4.5% of the weight of the original medicine; 80% ethanol is used as a binder, granulated with a 16-mesh sieve; dried at a...

Embodiment 3

[0044] Embodiment 3: by the weight proportion prescription of embodiment 3 in table 3, preparation method is with embodiment 2.

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PUM

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Abstract

The invention relates to a traditional Chinese preparation for treating chronic kidney failure and process for preparation, which is a prepared from Ligusticum wallichii, astragalus root, rhubarb horsetails, Chinese angelica root, epimeddium, dried rehmannia root, root of herbaceous peony, oriental water plantain rhizome, poria cocos wolf, pseudo-ginseng as raw material through disintegration, dissolvent extraction, ripening, sterilizing and granulation.

Description

technical field [0001] The invention relates to a medicine for treating chronic renal failure, specifically a Chinese patent medicine prepared from traditional Chinese medicines, and also relates to a preparation method of the medicine. Background technique [0002] Chronic renal failure is a group of clinical syndromes in which various chronic kidney diseases develop to a certain extent, leading to severe impairment of renal excretory function, internal environment stabilization function and endocrine function, and corresponding clinical manifestations. It is a group of common frequently-occurring diseases , the annual incidence rate is as high as 100 / 100,000. Although there are many drugs for the treatment of nephropathy, their curative effect is not good. Therefore, there is still a lack of effective prevention and treatment methods for the progressive damage of residual nephrons caused by various reasons, leading to chronic renal failure. It is an important research to...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/884A61K36/804A61K36/71A61K36/708A61K36/481A61K36/296A61K36/258A61K36/236A61K36/232A61K36/076A61P13/12
Inventor 袁发焕光丽霞
Owner NAT ENG RES CENT FOR MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
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