Medicine for treating cystic hyperplasia of mammary gland and preparation method thereof
A breast cystic hyperplasia and drug technology, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of unsuitability for routine use, large side effects, and long medication cycles, and achieves good analgesic effects, Strong effect of dispersing and removing blocks
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Embodiment 1
[0045] Embodiment 1, the present invention treats the preparation of breast cystic hyperplasia medicine
[0046] Drugs for the treatment of breast cystic hyperplasia, the prescription of which is as follows: Bupleurum 125g, Chishao 250g, Prunella vulgaris 300g, Oyster 300g, Angelica 250g, Tianqi 250g, Codonopsis 200g, Qingpi 125g, Tangerine core 200g, Shepherd’s purse 200g, Leulu 200g, Guijianyu 150g, Wangbuliuxing 200g.
[0047] The method for preparing the medicine for treating breast cystic hyperplasia comprises the following specific steps:
[0048] 1) Weigh the components in the above prescription, and perform routine pretreatment;
[0049] 2) Crush Bupleurum, Angelica, Leulu and Qingpi into coarse powder, then add it to water six times the total weight of Bupleurum, Angelica, Leulu and Qingpi, and distill for 5 hours to obtain about 1.2 g of volatile oil;
[0050] 3) β-CD cyclodextrin (or methyl cyclodextrin, hydroxypropyl cyclodextrin, hydroxyethyl cyclodextrin, cyclo...
Embodiment 2
[0058] Embodiment 2, the experiment that the medicine of the present invention treats cystic hyperplasia of mammary glands influences on estradiol benzoate mammary gland hyperplasia model rats
[0059] Adopt the medicine for the treatment of cystic hyperplasia of mammary glands prepared by embodiment 1 (clinical experiment is named as Chashao Ruhexiao tablet), carry out animal experiment to estradiol benzoate hyperplasia of mammary gland model rat, by contrast experiment, investigate medicine of the present invention to Therapeutic effects in rats with mammary gland hyperplasia. The specific experimental process is as follows:
[0060] Take 60 SD rats, female, with a body weight of 199.2±11.9g, and randomly divide them into 6 experimental groups, including the normal control group and the model control group. g / Kg, 11.88g / Kg three groups, Rupixiao tablet group administration dose is 1.04g / Kg group, each group of experimental rats 10.
[0061] Rats in the normal control group...
Embodiment 3
[0108] Embodiment 3, the experiment that the present invention treats cystic hyperplasia of mammary gland to the influence of qi stagnation and blood stasis model rats
[0109] Adopt the medicine for the treatment of cystic hyperplasia of mammary glands prepared by embodiment 1 (clinical experiment named as Chashao Ruhexiao tablet), carry out animal experiments to Qi stagnation and blood stasis model rats, by contrast experiment, investigate medicine of the present invention to test rats therapeutic effect. The specific experimental process is as follows:
[0110] Take 60 SD rats, female, with a body weight of 203.4±14.5g, and randomly divide them into 6 experimental groups, including the normal control group and the model control group. Three groups of Kg and 11.88g / Kg, the dosage of Rupixiao tablet is 1.04g / Kg group, each group has 10 experimental rats. Except for the normal control group, the other animals were fed with 200% rhubarb decoction 20ml / Kg. One hour later, the ...
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