2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre

A technology for oxidizing chromogenic bases and diaminopyridines, which can be used in cosmetics, organic chemistry, cosmetic preparations, etc., and can solve problems such as unstable light exposure.

Inactive Publication Date: 2003-06-25
LOREAL SA
View PDF15 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These compositions produce high intensit

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment example 1

[0629] Example example 1. Synthesis of 2-methoxy-6-(pyrrolidin-1-yl)-3-aminopyridine trisalt 1. Synthesis of 2-methoxy-3-nitro-6-(pyrrolidin-1-yl)pyridine

[0630] Add 4.79g (0.021mol) of 6-chloro-2-methoxy-3-nitropyridine, 40ml of ethanol and 3.5ml (0.042mol) of pyrrolidine into a fully equipped round bottom flask, and reflux under stirring The mixture was cooled to room temperature for 1 hour, and the crystalline product was filtered off, washed with diisopropyl ether, and dried to obtain 4.6 g of a yellow powder, yield: 96%.

[0631] The results of mass spectrometry and NMR spectroscopic analysis were consistent with the pre-conceived structure. 2. Synthesis of 2-methoxy-6-(pyrrolidin-1-yl)-3-aminopyridine trihydrochloride

[0632] 4 g (0.0179 mol) of 2-methoxy-3-nitro-6-(pyrrolidin-1-yl)pyridine synthesized above, 200 ml of ethanol and 0.8 g of palladium on carbon were charged into a 300 ml autoclave. The reduction mixture was stirred for 2 hours at a pres...

example 2

[0633] The results of mass spectrometry and NMR spectroscopic analysis were consistent with the pre-conceived structure. Example 2. 1-(5-Amino-6-methoxypyridin-2-yl)pyrrolidin-3-ol dihydrochloride 1. Synthesis of 1-(6-methoxy-5-nitropyridin-2-yl)pyrrolidin-3-ol

[0634] Add 2 g (0.0106 mol) of 6-chloro-2-methoxy-3-nitropyridine, 25 ml of ethanol and 1.9 g of 3-pyrrolidinol into a fully equipped round bottom flask, and stir the mixture at 50°C for 1 hours, the mixture was poured into ice water with stirring. The formed precipitate was filtered and dried to obtain 2 g of a yellow powder.

[0635] The results of mass spectrometry and NMR spectroscopic analysis were consistent with the pre-conceived structure. 2. Synthesis of 1-(5-amino-6-methoxypyridin-2-yl)pyrrolidin-3-ol dihydrochloride

[0636]2g (8.5mmol) 1-(6-methoxy-5-nitropyridin-2-yl) pyrrolidin-3-alcohol, 100ml ethanol and 0.5g palladium on charcoal join in the autoclave of 300ml, in The reduction reactio...

example 3

[0637] The results of mass spectrometry and nuclear magnetic resonance spectroscopic analysis were consistent with the pre-conceived structure. Example 3. 3-Amino-2-methoxy-6-(morpholin-4-yl)pyridine dihydrochloride 1. 4-(6-Methoxy-5-nitropyridin-2-yl)morpholine

[0638] Add 4g (0.02mol) of 6-chloro-2-methoxy-3-nitropyridine, 60ml ethanol and 3.69ml morpholine into a fully equipped round bottom flask, and reflux the mixture for 2 hours while stirring , then the mixture was poured into ice water with stirring, the formed precipitate was filtered and dried to give 2.2 g of yellow powder, yield = 50%.

[0639] The results of mass spectrometry and NMR spectroscopic analysis were consistent with the pre-conceived structure. 2. Synthesis of 3-amino-2-methoxy-6-(morpholin-4-yl)pyridine dihydrochloride

[0640] 2g (0.01mol) of 4-(6-methoxy-5-nitropyridin-2-yl) morpholine, 100ml of ethanol and 0.5g of palladium on charcoal were added to the 300ml autoclave at 8 The reduc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

This invention relates to dyeing compositions for the dyeing of keratin fibres comprising at least one oxidation base of the 2,5-diaminopyridine type, the use of the compositions for the dyeing of keratin fibres and a dyeing processes employing the compositions. Another object of the invention is to provide novel 2,5-diaminopyridine compounds for dyeing oxidation bases.

Description

field of invention [0001] One of the objects of the present invention is to provide a dyeing composition used for dyeing keratin fibers, which contains a 2,5-diaminopyridine-type oxidation base; the application also relates to the dyeing composition The use of the compound in the dyeing of keratin fibers and the method of dyeing with the composition; Another object of the present invention is to provide a class of novel 2,5-diaminopyridine compounds as oxidation bases. Background technique [0002] It is known to color keratin fibers, especially human, with dyeing compositions containing precursors of oxidative dyes, usually called oxidation bases (e.g. o- or p-phenylenediamines, o- or p-aminophenols and heterocyclic compounds). Colored hair. These colorless or faintly colored oxidation bases are combined with oxidizing substances to produce colored compounds through an oxidative chromogenic process. [0003] It is also known that the shades obtained from these oxidation b...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K8/00A61K8/20A61K8/22A61K8/31A61K8/33A61K8/34A61K8/40A61K8/41A61K8/49A61K8/66A61Q5/10C07D213/74C07D401/04
CPCA61K8/4926A61K8/415C07D213/74C07D401/04A61Q5/10A61K8/347A61K8/49
Inventor L·维达尔A·法利
Owner LOREAL SA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap