The purpose of the present invention is to provide a means for obtaining SMTP from a
fermentation product including SMTP via a method that can easily be scaled up; to provide an SMTP
crystallization method; or to provide a means for obtaining SMTP via a method including SMTP
crystallization. The present invention provides an SMTP production method including: a step I for putting a Stachybotrys microspora
fermentation product in contact with an aqueous
solvent having a pH of 9 or greater and obtaining an extract liquid including SMTP; a step II for supplying the extract liquid obtained in step I for purification and obtaining a purified product; and a step III for crystallizing the SMTP included in the purified product obtained in step II in a
crystallization solvent including one or more selected from the group consisting of
ethyl acetate,
butyl acetate,
acetone, 2-
butanone,
diisopropyl ether,
diethyl ether, methyl-tert-butyl
ether, and
acetonitrile. Alternatively, provided is an SMTP production method including a step for crystallizing SMTP having a purity of 70% or greater in a
solvent including one or more selected from the group consisting of
ethyl acetate,
butyl acetate,
acetone, 2-
butanone,
diisopropyl ether,
diethyl ether, methyl-tert-butyl
ether, and
acetonitrile. Alternatively, provided is an SMTP production method including putting a Stachybotrys microspora
fermentation product in contact with an aqueous solvent having a pH of 9 or greater and obtaining an extract liquid including SMTP.