Application of Nano copper powder for preparing medicine for prophylaxis of osteoporosis and bone fracture

A nano-copper powder, osteoporosis technology, applied in drug combination, powder delivery, bone diseases, etc., can solve problems such as poor absorption, calcium and phosphorus cannot be deposited, and the curative effect is difficult to last

Inactive Publication Date: 2003-07-23
马驷 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the current clinical calcium supplements are not well absorbed or calcium and phosphorus cannot be deposited in the bones after absorption.
Estrogen replacement therapy can directly improve bone metabolism in postmenopausal women and effectively prevent the progressive loss of bone in the first few years after menopause. However, short-term use of estrogen can hardly last long, and long-term use can easily lead to various complications, such as breast cancer. Cancer, endometrial cancer and other serious complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0101] Embodiment 1 Preparation of tablets

[0102] Take the following steps: take the nano copper powder, use the conventional tableting process, add dry binder and lubricant, mix evenly, directly compress into tablets, and sugar-coated to obtain tablets, so that each tablet contains 2.5 mg of nano copper powder .

[0103] Usage and dosage: Orally, one tablet at a time, twice a day.

Embodiment approach 2

[0104] Embodiment 2 Preparation of capsules

[0105] The following steps are adopted: take the nano-copper powder, sieving, add starch and mix evenly, and pack them into hard capsules to prepare capsules, each capsule containing 2.5 mg of nano-copper powder.

[0106] Usage and dosage: Orally, one capsule at a time, twice a day.

Embodiment approach 3

[0107] Embodiment 3 Preparation of granules

[0108] Take the following steps: take nano copper powder, add excipients powdered sugar and starch, sieving to make soft material, granulate, dry at low temperature, sizing, and pack into bags to obtain granules, each bag contains nano copper The powder is 2.5mg. Usage and dosage: Take warm boiled water, one bag at a time, twice a day.

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PUM

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Abstract

An application of nano (0.1-1000 nm) copper powder in preparing the medicines to prevent and treat osteoporosis and bone fracture is disclosed. Its advantages are sure curative effect and low toxic by-effect.

Description

Technical field [0001] The invention relates to the application of nano copper powder as a medicine for the prevention and treatment of osteoporosis and fractures. Background technique [0002] At present, osteoporosis is a systemic skeletal disease characterized by decreased bone mass and deterioration of bone microstructure, resulting in increased bone fragility and prone to fractures. With the increase of the elderly population, osteoporosis may become the enemy of most people's health in the future, so this high-incidence, metabolic bone disease is one of the problems currently being studied in the medical field. Osteoporosis is mainly divided into two categories: primary and secondary. Primary osteoporosis is a physiological change that occurs in bone tissue due to aging or women after menopause. Due to certain diseases (such as endocrine disorders, chronic diseases such as kidney, liver, and gastrointestinal calcium absorption disorders), malnutrition and drug-induced osteo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K33/34A61K45/06A61P19/08A61P19/10
CPCA61K45/06A61K9/14A61K33/34A61P19/08A61P19/10
Inventor 马驷李艳
Owner 马驷
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