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Eye drop of double rhizoma coptidis

A technology of Shuanghuanglian and eye drops, applied in the field of Shuanghuanglian eye drops, can solve the problems of Shuanghuanglian moisture absorption, caking and deterioration, unsatisfactory treatment effect, etc., so as to reduce the economic burden, increase the curative effect, and ensure the safety of medication. The effect of stability

Inactive Publication Date: 2003-11-19
SHENYANG XINGQI PHARM CO LTD
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  • Description
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AI Technical Summary

Problems solved by technology

[0003] The present invention is the first time that Shuanghuanglian is made into eye drops through the method of double packaging, which not only solves the problem of moisture absorption and caking of Shuanghuanglian, but also solves the problem of unsatisfactory therapeutic effect of systemic administration

Method used

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  • Eye drop of double rhizoma coptidis
  • Eye drop of double rhizoma coptidis

Examples

Experimental program
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Embodiment Construction

[0009] Shuanghuanglian Eye Drops [Prescription] Forsythia 100g

[0010] Honeysuckle 50g

[0011] Scutellaria baicalensis 50g

[0012] Make 200 eye drops solution Sodium Chloride 9.0g

[0013] Ethylparaben 0.5g

[0014] Make 1000ml [Preparation method] Take Scutellaria baicalensis, add water to decoct twice (8, 6 times the amount) for 1 hour each time, combine the filtrate, and adjust the pH value of the filtrate to 1.0-2.0 with 2mol / L hydrochloric acid solution. Incubate at 80°C for 30 minutes, let stand for 24 hours, filter, add 8 times the amount of water to the precipitate, stir, adjust the pH value to 6.0-7.0 with 40% sodium hydroxide solution, add the same amount of ethanol, stir to dissolve, filter, Adjust the pH of the filtrate to 2.0 with 2mol / L hydrochloric acid solution, keep it warm at 80°C for 30 minutes, let it stand for 12 hours, filter, wash the precipitate with ethanol until the pH value reaches 4.0, add 10 times the amount of w...

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Abstract

An eye drops "Shuanghuanglian" contains the aseptic powder of honeysuckle powder, coptis root and forsythia fruit and the solvent which is an isotonic solution of sodium chloride and hydroxyphenyl ethylester. Its advantages are high curative effect to virus infection of eye, and high safety.

Description

Technical field [0001] The active ingredient of the traditional Chinese medicine involved in the present invention—Shuanghuanglian—is made into eye drops for the first time, and is applied to the treatment of ophthalmic virus infection, aiming at improving the bioavailability of the active ingredient of the medicine, increasing the curative effect and the safety of medication. Background technique [0002] In the field of traditional Chinese medicine, the application history of Shuanghuanglian can be traced back to hundreds of years ago; in modern times, Shuanghuanglian is the first traditional Chinese medicine formula made into powder injection; its excellent therapeutic effect has been widely confirmed and recognized. But, in the application of Shuanghuanglian, there are following defects simultaneously: (1), Shuanghuanglian medicated powder is easy to absorb moisture and agglomerate denaturation, affects the curative effect and bioavailability and drug safety of medicine, ...

Claims

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Application Information

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IPC IPC(8): A61P27/02
Inventor 刘继东姚东民高峨宋长海
Owner SHENYANG XINGQI PHARM CO LTD
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