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Application of erychromycin lactobionate used as medicine for curing rhinitis and paranasual sinusitis

A technology for erythromycin lactobionate and sinusitis, which is applied in the application field of preparing erythromycin lactobionate as a medicine for treating rhinitis and paranasal sinusitis, and can solve problems such as easy recurrence, low cure rate, and few drugs, and the method is simple Easy to use, non-toxic and side effects, high safety effect

Inactive Publication Date: 2004-01-07
王军廷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Rhinitis and paranasal sinusitis are common diseases that are easy to recur and difficult to cure. The clinical manifestations are nasal congestion, loss of sense of smell, sneezing, runny nose, headache, dizziness, blurred vision, and memory loss. Auricularia and various compound prescriptions, western medicines include oxytetracycline, cotrimoxazole, penicillin and streptomycin, etc., because the way of administration is oral, intramuscular injection or infusion, so few medicines reach the diseased site, and the curative effect is poor; Drugs for nasal treatment include 1% ephedrine nasal drops, 0.05% nasal drops and 1% streptomycin nasal drops, etc., but the cure rate is very low
[0003] Erythromycin lactobionate is a macrolide antibiotic drug that has been used clinically. Some Gram-negative bacteria such as diplococcus, pertussis bacilli, and influenza bacilli also have antibacterial effects. Currently, only tablets and injections are available on the market, without nasal drops

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0008] Draw out 24±1ml, that is, 24±1g of water for injection with an empty needle, and add it into the bottle containing 0.3g of erythromycin lactobionate. Erythromycin lactobionate nasal drops were prepared.

[0009] In clinical, with the erythromycin lactobionate nasal drop that the present invention makes and with conventional medicine and treatment mode to the treatment situation of rhinitis, paranasal sinusitis disease as follows:

[0010] 1. Efficacy Judgment Criteria

[0011] 1) Cure: nasal congestion, sneezing, runny nose, loss of sense of smell, dry nasal cavity, headache, dizziness and other symptoms all disappeared. X-ray film showed that sinus gasification was normal, and there was no obvious abnormality in bone structure and sinus cavity. Three years later no recurrence;

[0012] 2), effective: nasal congestion, sneezing, runny nose, loss of sense of smell, dry nasal cavity, headache, dizziness and other symptoms basically disappeared. X-ray films showed that t...

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Abstract

The present invention relates to an application of erythromycin lactobionate in preparation of medicine for curing rhinitis and paranascsinusitis. It includes the erythromycin lactobionate nose dropsprepared by dissolving erythromycin lactobionate in the injection water, and its therapeutic effect is high.

Description

technical field [0001] The invention relates to the application of erythromycin lactobionate as a medicine for treating rhinitis and paranasal sinusitis. Background technique [0002] Rhinitis and paranasal sinusitis are common diseases that are easy to recur and difficult to cure. The clinical manifestations are nasal congestion, loss of sense of smell, sneezing, runny nose, headache, dizziness, blurred vision, and memory loss. Auricularia and various compound prescriptions, western medicines include oxytetracycline, cotrimoxazole, penicillin and streptomycin, etc., because the way of administration is oral, intramuscular injection or infusion, so few medicines reach the diseased site, and the curative effect is poor; The medicine of nasal treatment has 1% ephedrine nasal drops, 0.05% nasal drops and 1% streptomycin nasal drops etc., but the cure rate is all very low. [0003] Erythromycin lactobionate is a macrolide antibiotic drug that has been used clinically. Some gra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61P11/02
Inventor 王军廷
Owner 王军廷