Licorice root compound for treating acne

A technology of composition and licorice, which is applied in the direction of drug combination, medical preparations containing active ingredients, skin diseases, etc., can solve the problems of cumbersome use, high recurrence rate, cure rate, and overall unsatisfactory curative effect

Inactive Publication Date: 2005-01-05
北京海王中新药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A variety of drugs and physical therapy methods have certain effects on acne, but the overall curative effect such as cure rate and marked efficiency is not satisfactory; some use methods are cumbersome, and the medication time is very long; there are also common defects such as high recurrence rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Licorice 600g Angelica dahurica 400g Scutellaria baicalensis 300g Honeysuckle 500g Rhubarb 400g Aloe vera 300g

[0034] Crush the above drugs into coarse particles (3-5 meshes), add 5 times the amount of cold water to soak for 48 hours, filter the extract to get the filtrate. Add 3 times the amount of cold water to the filter residue and soak for 24 hours, and filter again to obtain the filtrate. The two filtrates were combined and concentrated by evaporation. After cooling, ethanol was added and placed at low temperature for 48 hours. The mixture was filtered and the filtrate was evaporated and concentrated again to obtain a brown viscous extract. At this time, the weight loss on drying of the extract was below 35%. The extract was concentrated and dried again to generate crude crystals for future use.

Embodiment 2

[0036] 840 grams of licorice, 450 grams of Angelica dahurica, 360 grams of skullcap, 480 grams of honeysuckle, 450 grams of rhubarb, 420 grams of aloe vera

[0037] Crush the above medicines into coarse grains (3-5 meshes), add 5 times the amount of clear water to soak for 4 hours, then heat with steam at 80-90°C for 4 hours, and filter to get the filtrate. Add 3 times the amount of clear water to the filter residue, heat it with steam at 80-90°C for 2 hours, and filter again to obtain the filtrate. The two filtrates were combined and concentrated by evaporation. After cooling, ethanol was added and placed at low temperature for 48 hours. The mixture was filtered and the filtrate was evaporated and concentrated again to obtain a brown viscous extract. At this time, the weight loss on drying of the extract was below 35%. The extract was concentrated and dried again to form crude crystals, which were then recrystallized in dilute ethanol solution to obtain refined products for f...

Embodiment 3

[0038] Embodiment 3 prepares ointment

[0039] Prescription: 10 grams of drug crystals prepared in Example 1 20 grams of triethanolamine

[0040] 50 grams of glycerin, 150 grams of stearic acid, 20 grams of lanolin

[0041] 250 grams of white petrolatum, 1 gram of ethyl hydroxybenzoate, distilled water to 1000 grams

[0042] Preparation method: Melt stearic acid on a water bath, add lanolin and white petrolatum, and heat to 80°C in a water bath; dissolve triethanolamine, glycerin, and ethylparaben in water, heat to 80°C on a water bath, and continue Gradually add the oil phase to the water phase under stirring, stir and condense to obtain an ointment, and finally add the finely ground drug crystals and stir evenly to obtain.

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PUM

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Abstract

A Chinese medicine in the form of ointment, lotion, or spray for preventing and treating acne is prepared from 6 Chinese-medicinal materials including liquorice root, dahurian angelica root, honeysuckle flower, aloe, etc.

Description

technical field [0001] The present invention relates to medicines or cosmetics for preventing and treating acne. Specifically, it is an external preparation made of botanicals such as licorice. Background technique [0002] Acne is a common condition among adolescents. Its essence is the chronic inflammation of hair follicles and sebaceous glands. After the inflammatory papules subside, it is easy to leave depressed scars and temporary pigmentation. [0003] At present, the medical circle still lacks powerful measures for the prevention of acne, and there is no special effect means for the treatment of acne. Various families adopt comprehensive measures such as anti-inflammatory, desinsection, inhibition of sebaceous gland secretion, and improvement of immune function. Various medicines and physical therapy methods have certain effects on acne, but the overall curative effects such as cure rate and marked efficiency are not satisfactory; Contents of the invention [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K9/12A61P17/10
Inventor 张振廷
Owner 北京海王中新药业股份有限公司
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