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'Duyiwei' soft capsule and its prepartion

A unique and soft capsule technology, applied in the preparation process of the preparation, in the field of unique soft capsule preparations, can solve problems such as difficult operation, numerous drug components, complicated technical solutions, etc., and achieve easy pipeline blockage and high product loading The difference is stable and the effect of reducing the dosage

Inactive Publication Date: 2005-01-26
代龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention patent application with the application number 03116422.6 "Bupleurum soft capsule preparation and its preparation method" also mentioned the use of various stabilizers including Tween-80, but all failed after the inventor tested according to his method , Analysis of the reasons: 1. The Bupleurum extract in this application is a volatile oil and an alcohol-soluble component, while the unique extract in the present invention is a water-soluble component. The difference in physical properties between the two determines the difference in the way in which the solvent is used. 2. In this application, there are many components of the drug, the technical scheme is complicated, and the operation is difficult

Method used

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  • 'Duyiwei' soft capsule and its prepartion
  • 'Duyiwei' soft capsule and its prepartion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Material ratio:

[0044] Duyiwei Extract Powder 2kg

[0045] Peanut oil 3.6kg

[0046] Span-80 0.03kg

[0047] crafting process:

[0048]Take 1.5kg of peanut oil, add Span-80, mix well, add the medicinal powder into the mixture, and stir while adding until completely mixed. Then add the remaining peanut oil and stir as you add until fully combined. Finally, put the mixture on a soft capsule filling machine, and press it into unique soft capsules.

Embodiment 2

[0050] Material ratio:

[0051] Duyiwei Extract Powder 2kg

[0052] soybean oil 2.8kg

[0053] Span-80 0.03kg

[0054] crafting process:

[0055] Take 1.5kg of soybean oil, add Span-80, mix well, add the medicinal powder into the mixture, and stir while adding until completely mixed. Then add the remaining peanut oil and stir as you add until fully combined. Finally, the mixture is ground in a colloid mill for 20 minutes, and the ground mixture is loaded into a soft capsule filling machine to be pressed into unique soft capsules.

Embodiment 3

[0057] Material ratio:

[0058] Duyiwei Extract Powder 2kg

[0059] Macrogol 400 3.4kg

[0060] Propylene glycol 0.3kg

[0061] Tween-80 0.03kg

[0062] crafting process:

[0063] Take 1.2 kg of polyethylene glycol 400, add propylene glycol and Tween-80, mix well, add the medicinal powder into the mixture, and stir while adding until completely mixed. Then add the remaining polyethylene glycol 400 and stir as you add until completely mixed. Finally, put the mixture on a soft capsule filling machine, and compress it into unique soft capsules.

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Abstract

Disclosed is a 'duyiwei' capsule, which is prepared from 'duyiwei' extract medicinal powder, plant oil, liquid state polyethylene glycol, propylene glycol, Span-80, and twain-80.

Description

technical field [0001] The invention discloses a pharmaceutical preparation, in particular a unique soft capsule preparation which takes the unique extract as an active ingredient, and also relates to a preparation process of the preparation. Background technique [0002] Soft capsules are a new dosage form developed after tablets and injections. They can quantitatively inject oily drugs, drug solutions or drug suspensions, pastes, and even drug powder into the film to form sizes and shapes. Assorted sealed capsules. This dosage form has several advantages: it can improve the strength and membrane barrier of the capsule; the drug is completely hermetically sealed, which can prevent oxidation and reduce moisture absorption, greatly improving the stability of the drug; the liquid in the soft capsule is made of Composed of diluent and active ingredient, the active ingredient is dissolved, suspended or emulsified in the diluent to form a uniform and stable system, thereby great...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61P29/00
Inventor 代龙
Owner 代龙
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