Coating, coated articles and methods of manufacture thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 美国英佛曼公司
- Publication Date
- 2005-03-02
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
[0001] Statement Regarding Federally Funded Research and Development
[0002] This invention was made with support under grant number NIH1R43AR47278-02 awarded by the National Institutes of Health. Accordingly, the US Government has rights in this invention. field of invention
[0003] This invention relates to apatite materials, and more particularly to coatings containing apatite. Background of the invention
[0004] Synthetic apatites, including hydroxyapatite (HA), Ca 10 (PO 4 ) 6 (OH) 2 , fluoroapatite Ca 10 (PO 4 ) 6 f 2 , or hydroxyfluoroapatite Ca 10 (PO 4 ) 6 (OH) 2-x f x (x<1) has the same biological apatite (Ca 10-x (HPO 4 ) x (OH) 2-x ) similar composition, while bioapatite is the main component of hard tissues such as bone. Due at least in part to their excellent osteoconductivity, apatites are used as coatings on metallic implants or prostheses (eg, prosthetic hips) in biofixation. This apatite coating has two interfaces, one with the tiss...