Improvement of method for preparing healthy qi strengthening, astragalus root and glossy privet fruit containing medicine

A technology of Zhenqi Fuzheng and medicine, which is applied in the field of preparation and improvement of Zhenqi Fuzheng medicine, which can solve the problems of inability to obtain oleanolic acid components and extract oleanolic acid, and achieve the effect of improving quality and improving therapeutic effect

Inactive Publication Date: 2005-06-01
甘肃扶正药物科技股份有限公司
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  • Summary
  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

However, the oleanolic acid component cannot be obtained in the obtained medicine extracted by the prior art
And still can't propose oleanolic acid from Ligustrum lucidum after many improvements to the water extraction process in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] Embodiment of the present invention and related detection data are provided below:

[0008] Weigh 1300-2000 grams of Astragalus membranaceus and 600-1000 grams of Ligustrum lucidum, and crush each drug into a coarse powder of less than 4 meshes. After mixing the crude drug powder, 3-8 times of 50-90% ethanol is used for reflux extraction for 1-4 hours, and then 3-8 times of 50-90% ethanol is used for reflux extraction for 1-4 hours. The filtrates extracted twice were combined, and the ethanol was recovered under reduced pressure until there was no ethanol smell in the medicine, and the alcohol extraction extract was obtained for future use.

[0009] Then add 3 to 8 times of water to decoct the dregs after alcohol extraction for 1 to 4 hours, filter the liquid and concentrate under reduced pressure to a relative density of 1.10 (60°C thermal measurement), add alcohol extraction extract, continue to reduce Concentrate under pressure until the relative density is 1.15-1.2...

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Abstract

The present invention relates to the improved preparation process of preparing available medicine Zhenqi medicine for strengthening body's resistance. The technological process of preparing available medicine Zhenqi medicine includes the steps of: alcohol reflux extraction of coarse powder of astragalus root and privet fruit, decompression distillation of the extracted liquid to obtain alcohol extracted extractum, decocting the medicine dregs, filtering to obtain filtrate, concentration and drying, mixing with the alcohol extracted extractum, further decompression drying, and spray drying to obtain dry extractum powder. The improved technological process can obtain the effective component oleanolic acid and higher content of astrasgaloside A.

Description

technical field [0001] The invention relates to the improvement of the preparation method of the existing drug "Zhenqi Fuzheng". Background technique [0002] Zhenqi Fuzheng medicine is produced by combining plant medicine Astragalus and Ligustrum lucidum in a ratio of nearly 2:1 (weight ratio), which is used to improve immunity and treat leukopenia caused by chemotherapy. In the prior art, the production process of Zhenqi strengthening medicine is to crush Astragalus membranaceus and Ligustrum lucidum into coarse powder, decoct with water, and then dry the water extract to obtain medicinal powder. Put the powder into capsules to make commercial medicines. Studies have shown that the active ingredients of Zhenqi strengthening medicine are astragaloside, polysaccharides, organic acids in Ligustrum lucidum, glycosides, terpenes, agarose, amino acids and trace elements. The study also found that oleanolic acid is the active ingredient in the organic acids of Ligustrum lucidum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K9/14A61P7/00A61P37/04
Inventor 席倬霞李建华高岩
Owner 甘肃扶正药物科技股份有限公司
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