Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Anticance auxiliary medicine using proto ginseng triol as effective component and its application

A technology of protopanaxatriol and anticancer drugs, which is applied in the directions of medical preparations containing active ingredients, organic active ingredients, drug delivery, etc.

Inactive Publication Date: 2005-06-08
SHANDONG GREENERY NATURAL MEDICINE RES & DEV
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no relevant reports on protopanaxatriol's effect on the immune function of tumor patients and on the attenuation and synergism of clinical radiotherapy and chemotherapy.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Anticance auxiliary medicine using proto ginseng triol as effective component and its application
  • Anticance auxiliary medicine using proto ginseng triol as effective component and its application
  • Anticance auxiliary medicine using proto ginseng triol as effective component and its application

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0011] Preparation Example 1 Preparation of 20(S)-Protopanaxatriol Soft Capsules

[0012] Weigh 100g of gelatin, 30g of glycerin and 130g of water. Get gelatin and add appropriate amount of water to make it absorb water and swell. In addition, put the glycerin and the remaining water in a glue pot and heat to 70~80°C, mix well, add the expanded gelatin, stir, and melt. Keep warm for 1~2 hours, let it stand still, make the foam rise, scrape off the floating foam, filter with clean white cloth, add 0.0075mgr Fe 2 o 3 powder, mix well, and keep warm for later use. The viscosity of the prepared glue is generally 2.8~3.2 degrees.

[0013] Weigh 10 g of protopanaxatriol and dissolve it in 90 g of polyethylene glycol, heat to fully dissolve it, and let it cool to room temperature.

[0014] Compressing soft capsules: Put the prepared gelatin glycerin and angelica oil into an automatic rotary capsule rolling machine, and press the temperature at 40-50°C to produce soft capsules co...

preparation example 220

[0015] Preparation Example 2 Preparation of 20(S)-protopanaxatriol freeze-dried powder for injection

[0016] Weigh 1.00g of 20(S)-protopanaxatriol, add 20ml of ethanol to completely dissolve the saponin, then add 40ml of glycerin and mix well. Add 0.20 g of tetracaine hydrochloride and 0.02 g of EDTA-2Na into 40 ml of water for injection to completely dissolve the auxiliary materials. And the above aqueous solution is added to the drug solution, and mixed evenly. Adjust the pH to 5.5±1.0 with 0.01mol / L sodium hydroxide and dilute hydrochloric acid. Add 0.1% needles and use activated carbon to incubate at 85°C for 15 minutes, filter through a G3 vertically fused glass funnel, and filter through a 0.22um microporous membrane. The filtrate was divided into 7ml vials, each containing 2ml.

[0017] The subpackaged injection is half-tamped, freeze-dried in a freeze dryer, and covered with aluminum to form a freeze-dried powder injection, 20mg / bottle.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

An auxiliary anticancer medicine for increasing the curative effect of other anticancer medicines, dicreasing their toxin, and preventing and treating the leukocytopenia caused by radiotherapy and chemicotherapy by injection or cral application features that its active component is protopanoxatriol.

Description

Technical field: [0001] The invention relates to an anti-cancer auxiliary drug for enhancing the curative effect of anti-cancer drugs, reducing the toxicity of anti-cancer drugs, preventing and treating leukopenia caused by radiotherapy and chemotherapy, and enhancing body fluid immune function, belonging to the medical field of cancer treatment. Background technique: [0002] Cancer has always been the enemy of human health. With the development of human science and technology, cancer cannot be completely conquered. On the contrary, its incidence is increasing year by year, and it has a tendency to become younger. In some countries, the morbidity and mortality of cancer have surpassed other diseases and have risen to the first place. In our country, at least 1.5 million people die of cancer every year. Cancer has caused wounds that are difficult to repair and heal both physically and mentally. The drug treatment of cancer has made remarkable progress in recent years, but m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K31/7048A61P37/04
Inventor 王振华马成俊何杰苟海涛傅风华
Owner SHANDONG GREENERY NATURAL MEDICINE RES & DEV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com