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Medicine for treating Parkinson's disease

A technology for Parkinson's disease and syndrome, applied in the field of drugs for the treatment of Parkinson's disease, can solve problems such as the inability to meet clinical needs, and achieve the effect of improving microcirculation disorders

Inactive Publication Date: 2005-07-06
西安亨通光华制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main domestic dopamine agonists levodopa and adamantane; dopa decarboxylase inhibitors such as carbidopa and other drugs are used clinically, but they still cannot meet the clinical needs
And the long-term use of the above-mentioned drugs can only eliminate the symptoms, side effects such as on-off phenomenon and automatism are more common, and patients need to take drugs for life to control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0109] 1 gram of mannan peptide produced by space-mutated strains; add appropriate amount of sweetener and essence; make 1000ml.

[0110] Dissolve 1g of mannan peptide produced by space-induced mutagenic strains and 0.10g of sodium saccharin with a small amount of purified water, add 0.1ml of essence, add purified water to 1000ml, stir well, filter, after passing the test, potting, and circulating steam to extinguish Bacteria at 121°C, 30 minutes.

Embodiment 2

[0112] Mannan peptide raw material solution 1000ml produced by space mutagenesis strains, activated carbon 0.25g, xylitol 0.8g, made into 1000ml.

[0113] Take 1000ml of the mannan peptide raw material solution produced by space mutagenic strains, add 0.25g of activated carbon, stir well, filter, add 0.5g of xylitol, stir well, after passing the test, potting, steam sterilization at 121°C, 30 minutes.

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PUM

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Abstract

The invention relates to a therapeutic medicine for Parkinson's syndrome, characterized in that: No.33 bacterial of alpha streptococcus hemolyticus is carried to outer space by go and back type deep space vehicle and heredity mutation thereof occurs under the special condition of outer space. After returning to earth, bacterial with positive mutation and stable heredity are optimized and be cultured and bio-fermented to prepare medicine for Parkinson's syndrome. Said bacterial has been preserved by China General Microbiological Culture Collection Center with serial number of CGMCCNo. 1082. Said medicine for the treatment of Parkinson's disease is oral liquid containing mannon peptide 0.8g to15.0g produced by outer space mutated serial in 1000 ml thereof.

Description

technical field [0001] The invention relates to a medicine, in particular to a medicine for treating Parkinson's syndrome. Background technique [0002] Parkinson's disease is a chronic progressive neurodegenerative disease, the main symptoms are tremor, muscle rigidity, slow movement and postural disturbance. The incidence rate is about 0.1-0.15%, and the number of patients in the world is about 4 million. [0003] There are about 1.5 million patients in our country. As the problem of population aging in our country becomes more serious, anti-Parkinson's syndrome drugs will have a larger market in our country. New anti-Parkinson’s drugs that have been marketed abroad in recent years mainly include: dopamine D2 agonist ropinirole; catechol O-methyltransferase inhibitor tolcapone; selective a2 / dopamine D2 agonist taclisol, etc. drug. The main domestic dopamine agonists levodopa, adamantane; dopa decarboxylase inhibitors such as carbidopa and oth...

Claims

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Application Information

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IPC IPC(8): A61K35/744A61K38/16A61P25/16C12N1/20C12P1/04
Inventor 赵恒刘恒
Owner 西安亨通光华制药有限公司
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