Cell-based detection and differentiation of disease states

A cell and disease technology, applied in the field of early detection, can solve the problem of not finding the magic bullet probe and so on
CN1695057AInactive Publication Date: 2005-11-09MONOGEN INC
2 Cites 27 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
MONOGEN INC
Publication Date
2005-11-09
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention provides a method for detecting and differentiating disease states with high sensitivity and specificity. The method allows for a determination of whether a cellbased sample contains abnormal cells and, for certain diseases, is capable of determining the histologic type of disease present. The method detects changes in the level and pattern of expression of the molecular markers in the cell-based sample. Panel selection and validation procedures are also provided.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] Cross References to Related Applications

[0002] This application is a continuation-in-part of U.S. Application Serial No. 10 / 095,298, filed March 12, 2002, which claims the benefit of U.S. Provisional Application Serial No. 60 / 274,638, filed March 12, 2001, the entire contents of which are incorporated herein as refer to. Background of the invention

[0003] The present invention relates to the early detection of general conditions in patients. The invention also relates to the differentiation of a particular pathology in its early and late stages.

[0004] Early detection of specific pathological conditions can greatly increase a patient's chance of survival through early diagnosis and early treatment, while the disease remains localized and its pathological effects are limited anatomically, physiologically, and clinically. The two main metrics that can be evaluated for any test or disease detection method are sensitivity (sensitivity=true pos...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More