Copolymerization derivative of poly-asparagic acid and synthetic method

A technology of polyaspartic acid and synthesis method, which is applied in the field of polyaspartic acid copolymer derivatives and its synthesis, can solve the problems of no significant improvement in product scale inhibition performance, slow reaction speed, unstable performance, etc., and achieve shortening The effect of reaction time, fast reaction speed and stable product performance

Inactive Publication Date: 2005-11-16
0 Cites 12 Cited by

AI-Extracted Technical Summary

Problems solved by technology

[0005] In view of the modification status of the above-mentioned polyaspartic acid, the present invention provides a polyaspartic acid copolymer derivative and its synthesis method, which can solve the problem of...
View more


A modified polyasparagic acid is prepared through preparing intermediate from asparagic acid, a compound, catalyst and solvent by radiating at 50Hz or 2450+/-50 Hz and 100-3000W for 1-40 min, and hydrolyzing.

Technology Topic

SolventAspartic acid


  • Copolymerization derivative of poly-asparagic acid and synthetic method


  • Experimental program(5)

Example Embodiment

[0007] Embodiment 1: The structural formula of the polyaspartic acid copolymer derivative of the present embodiment is:
[0008] In the formula, R is H, (CH 3 ) 2 CH, (CH 3 ) 2 CHCH 2 、CH 3 CH 2 CH(CH 3 ), HOCH 2 、CH 3 CH(OH), HSCH 2 or HOOCCH 2 CH 2 , the range of y/(y+x) is 0.1-0.9, and the range of x+y is 7-70. The optimum range of y/(y+x) in this embodiment is 0.1-0.5, and the optimum range of x+y is 9-30.

Example Embodiment

[0009] Specific embodiment two: this embodiment synthesizes polyaspartic acid copolymer derivatives according to the following steps: with aspartic acid and For raw materials, where R is H, (CH 3 ) 2 CH, (CH 3 ) 2 CHCH 2 、CH 3 CH 2 CH(CH 3 ), HOCH 2 、CH 3 CH(OH), HSCH 2 or HOOCCH 2 CH 2 , aspartic acid and The stoichiometric number is 1.0-99.9, using microwave technology, under the conditions of microwave frequency 915±50MHz or 2450±50MHz, microwave power 100-30000W, add catalyst and solvent to the reactant, and radiate reaction for 1-40min. The precursor of the polyaspartic acid copolymer derivative can be obtained, and the polyaspartic acid copolymer derivative can be obtained by hydrolyzing the precursor, wherein the stoichiometric number of the catalyst and the reactant is 0.01 to 1.00, and the chemical ratio of the solvent and the reactant The metering number is 0.10~9.99, and the reaction equation is as follows:
[0011] Aspartic acid Other amino acids Intermediates
[0012] Intermediate Polyaspartic acid copolymer derivative
[0013] R in the formula is mainly H, (CH 3 ) 2 CH, (CH 3 ) 2 CHCH 2 、CH 3 CH 2 CH(CH 3 ), HOCH 2 、CH 3 CH(OH), HSCH 2 or HOOCCH 2 CH 2; The range of y/(y+x) is 0.1-0.9, the optimal range is 0.1-0.5, and the range of x+y is 7-70, the optimal range is 9-30. In addition to the groups listed above, other groups of R also belong to the protection scope of the present invention, and these products can be prepared by the method of the present invention.
[0014] In the synthesis process, the reaction time will be shortened with the increase of power. Too short reaction time is not conducive to uniform reaction, so a stirring device is added, and the reaction time is not less than 3min. Too high power will lead to dark color of the reaction product, and also It may lead to carbonization of raw materials in a short time, so the most suitable power is 360~5000W. Under different conditions, light yellow, yellow, light brown, brown and dark brown products can be obtained, with a molecular weight of 600-20000. Raw material aspartic acid and The optimal stoichiometric number of the catalyst and the reactant is 1.0-9.9; the optimal stoichiometric number of the catalyst and the reactant is 0.01-0.5; the optimal stoichiometric number of the solvent and the reactant is 0.10-3.0; the optimal radiation reaction time is 3-3. 20min; the catalyst is phosphoric acid, sodium dihydrogen phosphate, sodium phosphate, sulfuric acid, sodium bisulfate, sodium sulfate, ammonium bisulfate, ammonium chloride, ammonium bicarbonate or ammonium carbonate; the boiling point of the organic solvent used is 150-300°C, Including dimethylformamide, dimethyl sulfoxide, propylene carbonate, sulfolane, dimethyl sulfone, methyl ethyl sulfone or diphenyl carbonate, etc.
[0015] Specific embodiment three: according to the stoichiometric number of aspartic acid and glutamic acid in table 1, add raw material to total 25g in the single-necked round bottom flask, take phosphoric acid as catalyst, the stoichiometric number of catalyst and raw material is 0.03, add 25ml of dimethylformamide, the reaction time is 5min under microwave radiation, the microwave power is 900W, and the light brown and fluffy product is obtained, and 40ml of 3mol/L NaOH is added to dissolve the product, and the pH of the solution is adjusted to be neutral, and the product is filtered. The filtrate was added to 250ml of absolute ethanol, the precipitate was collected, and vacuum-dried at 70°C to obtain a polyaspartic acid copolymer derivative.
[0016] Aspartate/Glutamate

Example Embodiment

[0017] Specific embodiment four: Add aspartic acid and serine to a total of 0.18mol in a single-mouthed round bottom flask, aspartic acid and serine stoichiometric number is 7: 3, with NaH 2 PO 4 As a catalyst, the stoichiometric number of the catalyst and the raw material is 0.05, add 16ml of dimethylformamide, the microwave power is 720W, and when the microwave radiation time (Table 2) is different, fluffy products of different colors are obtained, and 32ml of 3mol/L NaOH is added Dissolve the product, adjust the pH of the solution to be neutral, filter, add the filtrate of the product to 250 ml of absolute ethanol, collect the precipitate, and dry it in vacuum at 70° C. to obtain a polyaspartic acid copolymer derivative.
[0018] radiation time


no PUM

Description & Claims & Application Information

We can also present the details of the Description, Claims and Application information to help users get a comprehensive understanding of the technical details of the patent, such as background art, summary of invention, brief description of drawings, description of embodiments, and other original content. On the other hand, users can also determine the specific scope of protection of the technology through the list of claims; as well as understand the changes in the life cycle of the technology with the presentation of the patent timeline. Login to view more.

Similar technology patents

Method for removing bacterial endotoxin of use water refining raw medicine

InactiveCN108358926AProduct performance is stable

Transformer wind board

InactiveCN107545981AGood heat dissipationProduct performance is stable

Preparation method of high-strength and high-conductivity copper alloy load switch knife

ActiveCN114669960AProduct performance is stablelow cost

Inorganic-organic composite polymer phosphorus removal flocculating agent and preparation method thereof

ActiveCN109553170Ahigh molecular weightProduct performance is stable

A preparation method and equipment for a coating layer of an electric heating network

ActiveCN104492667Beasy to operateProduct performance is stable

Classification and recommendation of technical efficacy words

  • Improve anti-scaling performance
  • Product performance is stable

Terpolymer concentration slow-release anti-sludging agent and method of preparation thereof

InactiveCN107032509AImprove anti-scaling performanceStrong dispersion

Water treatment dirt dispersion agent and preparation method thereof

InactiveCN108946965AImprove anti-scaling performance

Alcohol-based fuel oil

ActiveCN103184081AProduct performance is stableClean and environmentally friendly oxygen content

Remote automobile control system and working method thereof

InactiveCN102662388ASimple structureProduct performance is stable

Fluorinated silicone lube oil synthetic method

InactiveCN1456647AProduct performance is stablePost-processing is simple

Starter output shaft and processing technology thereof

InactiveCN102852958AProduct performance is stableSolve the problem that the planetary gear shaft falls off

Lithium ion power low temperature cell

ActiveCN101615698AProduct performance is stableIncrease volume specific energy
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products