Medicinal composition of silibin

A technology of silibinin and its composition, which is applied in the pharmaceutical composition of silybin and its preparation field, can solve the problems of difficulty in preparing pure lecithin, increased preparation cost, unstable properties, etc., and achieve production cost Low, fat-soluble increase, the effect of reducing production cost
CN1714786AInactive Publication Date: 2006-01-04TIANJIN TASLY PHARMA CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TIANJIN TASLY PHARMA CO LTD
Publication Date
2006-01-04
Estimated Expiration
Not applicable · inactive patent
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Abstract

The present invention discloses a kind of medicinal composition containing silibin and its preparation process. Specifically, silibin and phosphatide are dissolved in organic solvent, the solution is heated and refluxed until becoming clear, and the solution is decompression concentrated to certain volume to obtain phosphatide dispersed matter, and the phosphatide dispersed matter is dried to obtain the medicinal composition.
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Description

technical field

[0001] The invention belongs to the field of medicine, and in particular relates to a medicinal composition of silybin and a preparation method thereof. Background technique

[0002] Milk thistle is a plant of Compositae native to southern Europe and North Africa. It is used in folk medicine to treat liver diseases. In 1968, Wagner et al. extracted a flavonoid compound 1 from it and named it silymarin (Sily marin). It has been proved that the main component of silymarin is silybin (Silybin, Sil) There are two isomers, Silydianin and Silychristinin. Experiments show that silybin has various pharmacological effects, which are briefly described as follows.

[0003] Liver protection

[0004] Silibinin can counteract the damage effect of various poisons and drugs on the liver. Such as Sil can reduce the toxic effect of carbon tetrachloride on the liver. As for the mechanism of hepatoprotective action, some studies suggest that Sil c...

Claims

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