Freeze dry tiopronin preparation without adjuvant for intravenous injection and its preparation process

A technique for tiopronin and freeze-dried preparations, which is applied in the field of freeze-dried preparations for intravenous injection of tiopronin and the preparation process, which can solve the problems of physical harm to patients, increased production costs of preparations, complexity of prescriptions and difficulty in drug quality control, etc. , to achieve the effects of guaranteed safety, easy control of preparation quality, and reduced production costs
CN1732912AInactive Publication Date: 2006-02-15苑振亭
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
苑振亭
Publication Date
2006-02-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a freeze dry tiopronin preparation without adjuvant for intravenous injection and its preparation process, wherein the preparation contains only medicinal Tiopronin but no addition agent of any kinds, one dosage unit of the freeze-dried preparation contains 10-1000mg of Tiopronin. The ratio of the medicament and water in the freeze-dried preparation can be 1:100 to 1:1, the purity of the Tiopronin medicament can be 85-100%.
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Description

Technical field:

[0001] The invention relates to the technical field of pharmaceutical preparations and preparation processes, and relates to a freeze-dried preparation of tiopronin for intravenous injection without auxiliary materials and a preparation process. Background technique:

[0002] Tiopronin, chemical name: N-(2-mercaptopropionyl)-glycine; English name: tiopronin,

[0003] The chemical structural formula is:

[0004]

[0005] As a liver function improving agent, tiopronin has achieved good results in the treatment of long-term clinical liver diseases. It was first launched in Japan, and then Germany, Italy, the United States, Switzerland and other countries have successively used it in clinical practice as a drug for improving liver function. Domestic research began in the early 1990s, and mass production began in the mid-1990s, and some products were launched. It is available as tablet (enteric-coated) and injection (lyophilized powder).

[0006] Tiopronin ...

Claims

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