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Piperacillin sodium and tazobactam sodium compound preparation for injection

The technology of piperacillin sodium and tazobactam sodium is applied in the field of compound preparations of anti-infective drugs, which can solve the problems of failing to achieve curative effect and the like, and achieve the effect of good therapeutic effect.

Inactive Publication Date: 2006-02-15
NORTH CHINA PHARMA GROUP CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the compound preparation has a better effect than a single drug, it still fails to achieve the best curative effect in clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Both piperacillin sodium and tazobactam sodium are sterile powders, fed at a weight ratio of 4:1, mixed evenly under aseptic conditions, and directly quantified under aseptic conditions according to the specification of 0.25 g / bottle Sub-package to make piperacillin sodium-tazobactam sodium compound preparation for injection.

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PUM

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Abstract

The invention discloses a compound preparation of piperacillin sodium and tazobactam sodium for injection, which comprises piperacillin sodium and tazobactam sodium by the weight ratio of 3-4:0.8-1.2. The preparation can be used for treating respiratory system infection, urological infection, otologia infection and skin infection.

Description

technical field [0001] The invention relates to pharmaceutical preparations, in particular to a compound preparation of anti-infection drugs. Background technique [0002] Piperacillin is a broad-spectrum semi-synthetic penicillin antibiotic, which has been widely used in clinic, but the increase of its drug-resistant bacteria limits the application of piperacillin. Blue-positive bacteria, Gram-negative bacteria and anaerobic bacteria all have good bactericidal effect. In order to enhance the synergistic effect of the drugs, at present, pharmaceutical manufacturers have prepared piperacillin sodium and tazobactam sodium for injection into composite preparations, and the dosage ratio of piperacillin sodium and tazobactam sodium is 8:1. Although the compound preparation has a better effect than a single drug, it still fails to achieve the best curative effect in clinical application. Contents of the invention [0003] The purpose of the present invention is to provide a pi...

Claims

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Application Information

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IPC IPC(8): A61K31/431A61P31/04A61K31/43
Inventor 吴金波
Owner NORTH CHINA PHARMA GROUP CORP
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